Evidence map›Paper›PMID 29075862›Full record

Trial reportEuropean journal of applied physiology2017

Concomitant external pneumatic compression treatment with consecutive days of high intensity interval training reduces markers of proteolysis.

Cody T Haun, Michael D Roberts, Matthew A Romero, Shelby C Osburn, James C Healy, Angelique N Moore, Christopher B Mobley, Paul A Roberson, Wesley C Kephart, Petey W Mumford and 3 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cody T HaunSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Michael D RobertsSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Matthew A RomeroSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Shelby C OsburnSchool of Kinesiology, Auburn University, Auburn, AL, USA.
James C HealyDepartment of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, Auburn, AL, 36832, USA.
Angelique N MooreDepartment of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, Auburn, AL, 36832, USA.
Christopher B MobleySchool of Kinesiology, Auburn University, Auburn, AL, USA.
Paul A RobersonSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Wesley C KephartSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Petey W MumfordSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Michael D GoodlettDepartment of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, Auburn, AL, 36832, USA.
David D PascoeSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Jeffrey S MartinSchool of Kinesiology, Auburn University, Auburn, AL, USA. jmartin@auburn.vcom.edu.ORCID http://orcid.org/0000-0001-6762-086X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the effects of external pneumatic compression (EPC) and sham when used concurrently with high intensity interval training (HIIT) on performance-related outcomes and recovery-related molecular measures.

methodsEighteen recreationally endurance-trained male participants (age: 21.6 ± 2.4 years, BMI: 25.7 ± 0.5 kg/m

resultsNo group × time interaction was observed for flexibility, PPT, or serum measures of creatine kinase (CK), hsCRP, and 8-isoprostane. However, there was a main effect of time for serum CK (p = 0.005). Change from PRE in 6-km run times at POST2 were not significantly different between groups. Significant between-groups differences existed for change from PRE in atrogin-1 mRNA (p = 0.018) at the POST1 time point (EPC: - 19.7 ± 8.1%, sham: + 7.7 ± 5.9%) and atrogin-1 protein concentration (p = 0.013) at the POST2 time point (EPC: - 31.8 ± 7.5%, sham: + 96.0 ± 34.7%). In addition, change from PRE in poly-Ub proteins was significantly different between groups at both the POST1 (EPC: - 26.0 ± 10.3%, sham: + 34.8 ± 28.5%; p = 0.046) and POST2 (EPC: - 33.7 ± 17.2%, sham: + 21.4 ± 14.9%; p = 0.037) time points.

conclusionsEPC when used concurrently with HIIT and in subsequent recovery days reduces skeletal muscle markers of proteolysis.

Indexed as

ProteolysisAdultC-Reactive ProteinCreatine KinaseDinoprostHigh-Intensity Interval TrainingHumansIntermittent Pneumatic Compression DevicesMaleMuscle ProteinsQuadriceps MuscleSKP Cullin F-Box Protein LigasesUbiquitination8-epi-prostaglandin F2alphaC-Reactive ProteinCreatine KinaseDinoprostFBXO32 protein, humanMuscle ProteinsSKP Cullin F-Box Protein LigasesEndurance exerciseHigh intensity interval trainingOxidative stressPneumatic compressionProteolysisRecoverySkeletal muscle

Identifiers

PMID29075862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.