ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2018
Occult spinal dysraphisms in newborns with skin markers: role of ultrasonography and magnetic resonance imaging.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Incidence of Occult Spinal Dysraphism Among Infants With Cutaneous Stigmata and Proportion Managed With Neurosurgery: A Systematic Review and Meta-analysis.JAMA network open · 2020Pooled it
- Evaluating the Diagnostic Utility of Spinal Ultrasound in Neonates With a Simple Sacral Dimple: An Eight-Year Retrospective Study.Journal of medical radiation sciences · 2026Article
- Efficacy of spinal ultrasonography just before caudal epidural block for identifying tethered cord syndrome in urological cases with sacral dimples: a retrospective descriptive study.Journal of anesthesia · 2025Article
- Cloacal Dysgenesis Sequence in a Preterm Neonate.The American journal of case reports · 2024Article
- International Consensus Statement on the Radiological Evaluation of Dysraphic Malformations of the Spine and Spinal Cord.AJNR. American journal of neuroradiology · 2024Review
- Comparison of Ultrasonographic Findings between Patients with Tethered Cord Syndrome and Healthy Children.Iranian journal of medical sciences · 2023Article
- Ultrasound of congenital spine anomalies.Pediatric radiology · 2021Review
- Risk of occult spinal dysraphism based on lumbosacral cutaneous manifestations.SAGE open medicine · 2021Article
- Determining the optimal timing of screening spinal cord ultrasonography to detect filum terminale lipoma in infants.Ultrasonography (Seoul, Korea) · 2020Article
- Acute presentations of intradural lipomas: case reports and a review of the literature.BMC neurology · 2019Review
- Diagnosis and management of individuals with Fetal Valproate Spectrum Disorder; a consensus statement from the European Reference Network for Congenital Malformations and Intellectual Disability.Orphanet journal of rare diseases · 2019Article
- Spinal cord ultrasonography of the newborn.Journal of ultrasound · 2019Review
- Dorsal midline cutaneous stigmata associated with occult spinal dysraphism in pediatric patients.Korean journal of pediatrics · 2019Article
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this paper is to investigate occult spinal dysraphisms (OSD) using lumbar ultrasonography (LUS) in newborns presenting with specific skin markers or sacrococcygeal dimple.
methodFrom 2012 to 2015, we performed LUS in newborns with cutaneous stigmata and/or sacroccygeal dimple. Magnetic resonance imaging (MRI) was performed in all patients with abnormal ultrasound or features of neurological involvement in order to detect spinal lesions.
resultsWe prospectively evaluated 475 newborns who presented cutaneous stigmata performing LUS during their 4 weeks of life though 439 completed the study. All patients had a follow-up of almost 12 months. Of these, 39 presented abnormal ultrasonography and underwent MRI. In this group, spinal dysraphism was confirmed in 12 patients. When considering skin markers, dermal sinus correlated with higher risk of spinal cord lesions, on the other hand the presence of simple sacral dimple alone denoted a very low risk of occult spinal dysraphism. The simultaneous presence of more skin markers and/or the presence of lumbar ultrasonography abnormality regarding the level of the conus, pulsatility, and the position of the cord, thickness of the filum terminale, or the presence of an intratecal mass, lipoma, or dermal sinus tract indicated the necessity to perform MRI in order to detect spinal cord abnormalities because of higher risk of spinal lesions.
conclusionLUS in newborns with specific skin markers is a valid method to select patients in which MRI can be performed to detect OSD. The presence of a simple sacral dimple alone is a negligible marker for occult neural pathology while the presence of isolated dermal sinus or more than one cutaneous marker could be considered indicative of higher risk of spinal dysraphism.
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