Evidence map›Paper›PMID 29075831›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2018

Repeatability of tumour hypoxia imaging using [

Antti Silvoniemi, Sami Suilamo, Timo Laitinen, Sarita Forsback, Eliisa Löyttyniemi, Samuli Vaittinen, Virva Saunavaara, Olof Solin, Tove J Grönroos, Heikki Minn

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 46 citations in OpenAlex.

  1. Prospective Evaluation of a Tumor Control Probability Model Based on DynamicJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Synthesis of a 2-nitroimidazole derivative N-(4-[EJNMMI radiopharmacy and chemistry · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. The feasibility of [EJNMMI research · 2020
    Article
  15. Article
  16. Theranostics · 2020
    Article
  17. Oxygen-Guided Radiation Therapy.International journal of radiation oncology, biology, physics · 2019
    Article
  18. Longitudinal PET imaging of tumor hypoxia during the course of radiotherapy.European journal of nuclear medicine and molecular imaging · 2018
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Antti SilvoniemiTurku PET Centre, University of Turku, P.O. BOX 52, FI-20521, Turku, Finland. anmisi@utu.fi.ORCID http://orcid.org/0000-0001-9655-1410
Sami SuilamoDepartment of Oncology and Radiotherapy, Turku University Hospital, P.O. BOX 52, FI-20521, Turku, Finland.
Timo LaitinenTurku PET Centre, University of Turku, P.O. BOX 52, FI-20521, Turku, Finland.
Sarita ForsbackTurku PET Centre, University of Turku, P.O. BOX 52, FI-20521, Turku, Finland.
Eliisa LöyttyniemiDepartment of Biostatistics, University of Turku, Turku, Finland.
Samuli VaittinenDepartment of Pathology, Turku University Hospital, P.O. BOX 52, FI-20521, Turku, Finland.
Virva SaunavaaraTurku PET Centre, University of Turku, P.O. BOX 52, FI-20521, Turku, Finland.
Olof SolinTurku PET Centre, University of Turku, P.O. BOX 52, FI-20521, Turku, Finland.
Tove J GrönroosTurku PET Centre, University of Turku, P.O. BOX 52, FI-20521, Turku, Finland.
Heikki MinnTurku PET Centre, University of Turku, P.O. BOX 52, FI-20521, Turku, Finland.
University of Turku · FITurku University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHypoxia contributes to radiotherapy resistance and more aggressive behaviour of several types of cancer. This study was designed to evaluate the repeatability of intratumour uptake of the hypoxia tracer [

methodsTen patients with newly diagnosed head and neck cancer (HNC) received three static PET/CT scans before chemoradiotherapy: two with [

resultsIn 10 paired [

conclusionPretreatment [

Indexed as

Fluorine RadioisotopesHydrocarbons, FluorinatedPositron Emission Tomography Computed TomographyTumor HypoxiaAgedEtanidazoleFemaleFluorocarbonsHead and Neck NeoplasmsHumansMaleMiddle AgedNeoplasm StagingProspective Studies2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamideEtanidazoleFluorine-18Fluorine RadioisotopesFluorocarbonsHydrocarbons, Fluorinated18F-EF5Head and neck cancerHypoxiaPetRepeatability

Identifiers

PMID29075831
PMCPMC5745570
OpenAlexW2765954605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.