Evidence map›Paper›PMID 29075628›Full record

ArticleFrontiers in medicine2017

Selective Essential Oils from Spice or Culinary Herbs Have High Activity against Stationary Phase and Biofilm

Jie Feng, Shuo Zhang, Wanliang Shi, Nevena Zubcevik, Judith Miklossy, Ying Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Bacterial persisters: molecular mechanisms and therapeutic development.Signal transduction and targeted therapy · 2024
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  5. Secreted Metabolites fromMicroorganisms · 2024
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  6. Review
  7. Article
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  9. Article
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  11. Article
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  19. Review
  20. Antibiotic in myrrh fromFuture science OA · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jie FengDepartment of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Shuo ZhangDepartment of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Wanliang ShiDepartment of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Nevena ZubcevikDepartment of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Charlestown, MA, United States.
Judith MiklossyInternational Alzheimer Research Centre, Prevention Alzheimer International Foundation, Martigny-Croix, Switzerland.
Ying ZhangDepartment of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Johns Hopkins University · USHarvard University · USPrevention Alzheimer International Foundation · CH

Funding

Pyrazinamide and Trans-Translation in Mycobacterium tuberculosisR01AI099512 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ZHANG, YING · 2012 to 2015
$1.7M
Toxin-antitoxins & RpsA in TB drug resistance & persistence with HIVR21AI108535 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ZHANG, YING · 2014 to 2015
$443k
NIAID NIH HHS R01 AI099512NIAID NIH HHS R21 AI108535
6 · The paper itself

Abstract

Although the majority of patients with acute Lyme disease can be cured with the standard 2-4 week antibiotic treatment, about 10-20% of patients continue suffering from chronic symptoms described as posttreatment Lyme disease syndrome. While the cause for this is debated, one possibility is that persister bacteria are not killed by the current Lyme antibiotics and remain active in the system. It has been reported that essential oils have antimicrobial activities and some have been used by patients with persisting Lyme disease symptoms. However, the activity of essential oils against the causative agent

Indexed as

biofilmBorrelia burgdorfericarvacrolessential oilspersisters

Identifiers

PMID29075628
PMCPMC5641543
OpenAlexW2756763970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.