Evidence map›Paper›PMID 29075559›Full record

SynthesisBrain and behavior2017

The association between lesion location, sex and poststroke depression: Meta-analysis.

Ying Zhang, Hui Zhao, Yan Fang, Suishan Wang, Haiyun Zhou

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Poststroke depression among stroke survivors in Sub-Himalayan region.Journal of family medicine and primary care · 2020
    Article
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  16. Article
  17. Article
  18. Post-Stroke Depression.Materia socio-medica · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ying ZhangDepartment of Neurology The First People's Hospital of Shangqiu Henan China.ORCID 0000-0002-3866-5679
Hui ZhaoDepartment of Cardiology The First People's Hospital of Shangqiu Henan China.
Yan FangDepartment of Neurology The First People's Hospital of Shangqiu Henan China.
Suishan WangDepartment of Neurology The First People's Hospital of Shangqiu Henan China.
Haiyun ZhouDepartment of Neurology The First People's Hospital of Shangqiu Henan China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoststroke depression (PSD) is a common form of stroke patients. Whether the risk of PSD is influenced by the stroke lesion location and sex remains a matter of debate. The objective of this study was to examine the association between the risk of PSD and the stroke lesion location and sex by performing a systematic meta-analysis.

methodsSubgroup analyses were performed according to the time interval after stroke onset to assessment for PSD. A total of 31 reports involving 5,309 subjects (for lesion location analysis) and 5,489 subjects (for sex analysis) suffering from stroke were included in this meta-analysis.

resultsThe pooled odds ratio (OR) of PSD after a left-hemisphere stroke, compared with a right-hemisphere stroke was 1.11 (95% confidence interval [CI] 0.82-1.49) and OR of PSD after a male stroke, compared with a female stroke was 0.68 (95% CI 0.58-0.81). Subacute poststroke subgroup (1-6 months) significantly favored PSD occurring after a left hemisphere stroke (OR = 1.50, 95% CI 1.21-1.87). Furthermore, there was a statistically significant association between PSD and female stroke for studies with acute poststroke group (OR = 0.73, 95% CI 0.62-0.86) and subacute poststroke stroke phase (OR = 0.69, 95% CI 0.56-0.86).

conclusionsThis systematic review suggests that patients with left hemisphere stroke may be more susceptible to PSD during subacute phase of stroke and female stroke may be more susceptible to PSD during acute and subacute phase of stroke.

Indexed as

DepressionStrokeAgedDominance, CerebralHumansStatistics as Topicmeta‐analysispoststroke depressionsexsystematic reviewthe stroke lesion location

Identifiers

PMID29075559
PMCPMC5651383

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.