Evidence map›Paper›PMID 29075354›Full record

ArticleJournal of chemical biology2017

Design and synthesis of an indol derivative as antibacterial agent against

Hau-Heredia Lenin, Figueroa-Valverde Lauro, Rosas-Nexticapa Marcela, Herrera-Meza Socorro, López-Ramos Maria, Díaz-Cedillo Francisco, García-Cervera Elodia, Pool-Gómez Eduardo, Paat-Estrella Josefa, Cauich-Carrillo Regina and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Preparation and antimicrobial activity of Mono-, Bis, and Tris-4,9-Dihydroxy-7,7-Dimethyl-5-(mono-substituted-aryl)-Hexahydro-Indeno[1,2-b]Indole-9,10-Dione derivatives.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hau-Heredia LeninLaboratory of Investigation, Faculty Chemical-Biological Sciences, University Autonomous of Campeche, Agustin Melgar s/n, C.P. 24039 Bellavista, Campeche Mexico.
Figueroa-Valverde LauroLaboratory of Investigation, Faculty Chemical-Biological Sciences, University Autonomous of Campeche, Agustin Melgar s/n, C.P. 24039 Bellavista, Campeche Mexico.
Rosas-Nexticapa MarcelaFacultad de Nutrición, Universidad Veracruzana, Médicos y Odontólogos s/n, 91010 Xalapa, Veracruz Mexico.
Herrera-Meza SocorroInstituto de Investigaciones Psicológicas, Universidad Veracruzana, Av. Dr. Luis Castelazo Ayala s/n Col Industrial Animas, C.P. 91190 Xalapa, Veracruz Mexico.
López-Ramos MariaLaboratory of Investigation, Faculty Chemical-Biological Sciences, University Autonomous of Campeche, Agustin Melgar s/n, C.P. 24039 Bellavista, Campeche Mexico.
Díaz-Cedillo FranciscoEscuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional Col. Santo Tomas, Prol. Carpio y Plan de Ayala s/n, D.F. C.P. 11340 México, Mexico.
García-Cervera ElodiaLaboratory of Investigation, Faculty Chemical-Biological Sciences, University Autonomous of Campeche, Agustin Melgar s/n, C.P. 24039 Bellavista, Campeche Mexico.
Pool-Gómez EduardoLaboratory of Investigation, Faculty Chemical-Biological Sciences, University Autonomous of Campeche, Agustin Melgar s/n, C.P. 24039 Bellavista, Campeche Mexico.
Paat-Estrella JosefaLaboratory of Investigation, Faculty Chemical-Biological Sciences, University Autonomous of Campeche, Agustin Melgar s/n, C.P. 24039 Bellavista, Campeche Mexico.
Cauich-Carrillo ReginaLaboratory of Investigation, Faculty Chemical-Biological Sciences, University Autonomous of Campeche, Agustin Melgar s/n, C.P. 24039 Bellavista, Campeche Mexico.
Euan-Hau SaidyLaboratory of Investigation, Faculty Chemical-Biological Sciences, University Autonomous of Campeche, Agustin Melgar s/n, C.P. 24039 Bellavista, Campeche Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several indole derivatives with antibacterial activity have been prepared using different protocols; however, some require special reagents and conditions. The aim of this study involved the synthesis of some indole derivatives using estrone and OTBS-estrone as chemical tools. The synthesis of the indole derivatives involves reactions such as follows: (1) synthesis of two indol derivatives (

Indexed as

AntibacterialBenzaldehydeEstroneHexyneIndoleSynthesis

Identifiers

PMID29075354
PMCPMC5639818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.