Evidence map›Paper›PMID 29075345›Full record

Observational studyJournal of medicine and life

Factors that influence the severity of post-stroke depression.

S Ilut, A Stan, A Blesneag, V Vacaras, S Vesa, L Fodoreanu

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Social Support and Depression among Stroke Patients: A Topical Review.International journal of environmental research and public health · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. (Biological psychiatry global open science · 2021
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

S IlutDepartment of Neurology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
A StanDepartment of Neurology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
A BlesneagDepartment of Neurology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
V VacarasDepartment of Neurology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
S VesaDepartment of Pharmacology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
L Fodoreanu"Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this paper was to investigate whether the extent of neurological impairment, the location of ischemic lesions due to stroke are associated with the severity of post-stroke depression. MATERIALS AND

methodsThe study included 82 patients, who were diagnosed with acute ischemic stroke and post-stroke depression and were admitted to the Neurology Clinic of Cluj-Napoca County Emergency Hospital between 2009 and 2011. A head MRI was performed with a 1.5 Tesla. Psychometric assessment was performed by using several scales, including the Beck Depression Inventory and the Mini-Mental State Examination. The National Institutes of Health Stroke Scale (NIHSS) and the Barthel Index of Activities of Daily Living were used to produce a complete neurological assessment.

resultsPatients with severe depression had a lower score on the Quality of Life Scale (QOLS) and higher scores for the Barthel index, NIHSS and MMSE. A stroke located in the basal nuclei increased the probability of severe depression. The patients with fewer lesions (1-2) had a greater chance of developing mild or moderate depression compared to the patients with 3-4 lesions. A frontal localization of the stroke was almost twice as common in patients with severe depression. If the stroke affected the left hemisphere, there was a higher probability of severe depression. In multivariate analysis, a basal nuclei lesion, a left hemisphere stroke location, and an NIHSS score >11 were all independently associated with severe depression.

conclusionThe location of the stroke and the NIHSS score could be related to the severity of post-stroke depression.

Indexed as

Severity of Illness IndexAgedDepressionFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisRisk FactorsROC CurveStrokeStroke Rehabilitationfrontal lesionNIH stroke scalepost-stroke depressionstroke

Identifiers

PMID29075345
PMCPMC5652262
OpenAlexW2925331879

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.