Evidence map›Paper›PMID 29075343›Full record

Trial reportJournal of medicine and life

Efficacy and safety of Cerebrolysin treatment in early recovery after acute ischemic stroke: a randomized, placebo-controlled, double-blinded, multicenter clinical trial.

K Gharagozli, A A Harandi, S Houshmand, N Akbari, D F Muresanu, J Vester, S Winter, H Moessler

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Cerebrolysin for acute ischaemic stroke.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Pooled it
  3. Cerebrolysin for acute ischaemic stroke.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Cerebrolysin for vascular dementia.The Cochrane database of systematic reviews · 2019
    Pooled it
  5. Safety and efficacy of Cerebrolysin in early post-stroke recovery: a meta-analysis of nine randomized clinical trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

K GharagozliDepartment of Neurology, Shahid Beheshti Medical University, Teheran, Islamic Republic of Iran.
A A HarandiDepartment of Neurology, Shahid Beheshti Medical University, Teheran, Islamic Republic of Iran.
S HoushmandDepartment of Neurology, Shahid Beheshti Medical University, Teheran, Islamic Republic of Iran.
N AkbariDepartment of Neurology, Shahid Beheshti Medical University, Teheran, Islamic Republic of Iran.
D F MuresanuDepartment of Clinical Neurosciences, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
J VesterDepartment of Biometry and Clinical Research, IDV Data Analysis and Study Planning, Krailling, Germany.
S WinterEVER Neuro Pharma GmbH, Unterach, Austria.
H MoesslerCOMAMO Lifesciences GmbH, Mondsee, Austria.
EVER Neuro Pharma (Austria) · ATIuliu Hațieganu University of Medicine and Pharmacy · ROZimmer Biomet (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Recovery of FunctionAgedAged, 80 and overAmino AcidsBrain IschemiaDouble-Blind MethodFemaleHumansMaleMiddle AgedNeuroprotective AgentsPlacebosProspective StudiesRisk FactorsStrokeTreatment OutcomeAmino AcidscerebrolysinNeuroprotective AgentsPlacebosCerebrolysinearly recoveryischemic strokeRCTrehabilitation

Identifiers

PMID29075343
PMCPMC5652261
OpenAlexW2766116432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.