Evidence map›Paper›PMID 29075289›Full record

ArticleGastroenterology research and practice2017

Serology of Viral Infections and Tuberculosis Screening in an IBD Population Referred to a Tertiary Centre of Southern Italy.

Marco Ardesia, Giuseppe Costantino, Placido Mondello, Angela Alibrandi, Walter Fries

Abstract read
In one paragraph

Article in Gastroenterology research and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco ArdesiaDepartment of Clinical and Experimental Medicine, Clinical Unit for Chronic Bowel Disorders, IBD-Unit, University of Messina, Messina, Italy.ORCID 0000-0002-2701-2816
Giuseppe CostantinoDepartment of Clinical and Experimental Medicine, Clinical Unit for Chronic Bowel Disorders, IBD-Unit, University of Messina, Messina, Italy.
Placido MondelloInfectious Diseases, Department of Human Pathology, University Hospital of Messina, Messina, Italy.
Angela AlibrandiDepartment of Economics, University of Messina, Messina, Italy.
Walter FriesDepartment of Clinical and Experimental Medicine, Clinical Unit for Chronic Bowel Disorders, IBD-Unit, University of Messina, Messina, Italy.ORCID 0000-0001-6159-7478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the introduction of more potent immunosuppressive agents in inflammatory bowel disease, prevention of opportunistic infections has become necessary by introducing screening programs. Prevalence of the most important infectious agents may vary in different geographical areas. The aim of our study was to assess the immune status for hepatitis B, varicella, mononucleosis, and cytomegalovirus infection together with the determination of the hepatitis C and tuberculosis status in Southern Italy.

methodsPrevalence of latent tuberculosis, together with serology of hepatitis B and C, Epstein-Barr virus, varicella zoster, and cytomegalovirus were collected by analysing retrospectively the clinical charts of IBD patients. Data were integrated with demographic and clinical features.

resultsData from 509 IBD patients divided in two age groups showed a prevalence of HBV infection in nonvaccinated patients of 9%. Seroprotection (HBsAb) in vaccinated IBD patients was lower (

conclusionsIn younger patients, high susceptibility rates for primary herpesvirus infections should determine the choice of treatment. Loss of HBV seroprotection in already vaccinated patients should be considered for booster vaccination programs.

Identifiers

PMID29075289
PMCPMC5623777

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