Evidence map›Paper›PMID 29075269›Full record

ArticleFrontiers in immunology2017

Galectin-1 Impairs the Generation of Anti-Parasitic Th1 Cell Responses in the Liver during Experimental Visceral Leishmaniasis.

Patrick T Bunn, Marcela Montes de Oca, Fabian de Labastida Rivera, Rajiv Kumar, Chelsea L Edwards, Rebecca J Faleiro, Susanna S Ng, Meru Sheel, Yulin Wang, Fiona H Amante and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. The role of galectins in immunity and infection.Nature reviews. Immunology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Patrick T BunnQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Marcela Montes de OcaQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Fabian de Labastida RiveraQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Rajiv KumarDepartment of Biochemistry, Banaras Hindu University, Varanasi, India.
Chelsea L EdwardsQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Rebecca J FaleiroQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Susanna S NgQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Meru SheelQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Yulin WangQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Fiona H AmanteQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Ashraful HaqueQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Christian R EngwerdaQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
QIMR Berghofer Medical Research Institute · AUGriffith University · AUBanaras Hindu University · INUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many infectious diseases are characterized by the development of immunoregulatory pathways that contribute to pathogen persistence and associated disease symptoms. In diseases caused by intracellular parasites, such as visceral leishmaniasis (VL), various immune modulators have the capacity to negatively impact protective CD4

Indexed as

galectin-1inflammationLeishmaniaT cellsvisceral leishmaniasis

Identifiers

PMID29075269
PMCPMC5643427
OpenAlexW2762924822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.