Evidence map›Paper›PMID 29075101›Full record

ArticleDrug design, development and therapy2017

Anti-proliferative, apoptotic induction, and anti-migration effects of hemi-synthetic 1'

Su Ki Liew, Mohamad Nurul Azmi, Lionel LA In, Khalijah Awang, Noor Hasima Nagoor

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Study of Cytotoxicity of Pyrrolo[3,4-International journal of molecular sciences · 2026
    Article
  2. Review
  3. Article
  4. Chemical Composition and Anti-Lung Cancer Activities ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Identification of Spiro-Fused Pyrrolo[3,4-International journal of molecular sciences · 2021
    Article
  12. Review
  13. Article
  14. Silence of α1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Su Ki LiewInstitute of Biological Science (Genetics & Molecular Biology), Faculty of Science, University of Malaya, Kuala Lumpur.
Mohamad Nurul AzmiSchool of Chemical Sciences, Universiti Sains Malaysia, Penang.
Lionel LA InDepartment of Biotechnology, Faculty of Applied Sciences, UCSI University.
Khalijah AwangCentre for Natural Product Research and Drug Discovery (CENAR).
Noor Hasima NagoorInstitute of Biological Science (Genetics & Molecular Biology), Faculty of Science, University of Malaya, Kuala Lumpur.
University of Malaya · MYDrug Discovery Laboratory (Norway) · NOUCSI University · MYUniversiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nine analogs of 1'

Indexed as

Antineoplastic AgentsApoptosisBenzyl AlcoholsBlotting, WesternBreast NeoplasmsCell Line, TumorCell MovementCell ProliferationDNA FragmentationEpithelial CellsFemaleHumansInhibitory Concentration 50Neoplasms1'-acetoxychavicol acetateAntineoplastic AgentsBenzyl Alcohols1′S-1′-acetoxychavicol acetateACAACA hemi-synthetic analogsDNA fragmentationintegrin β1 signaling pathwayMTT assaytriple-negative breast cancerWestern blotwound-healing assay

Identifiers

PMID29075101
PMCPMC5609789
OpenAlexW2754817487

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.