ArticleScientific reports2017
Larval honey bees infected with Nosema ceranae have increased vitellogenin titers as young adults.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 32 citations in OpenAlex.
- Microsporidia: evolution, infection mechanisms and host impact.Nature reviews. Microbiology · 2026Review
- Innate defense mechanisms against Nosema ceranae in hygienic honey bee (Apis mellifera) colonies.PloS one · 2026Article
- An Innovative Multi-Omics Approach Reveals the Interactions Between Honeybees and Their Environment.Animals : an open access journal from MDPI · 2025Article
- Article
- Influence of Age of Infection on the Gut Microbiota in Worker Honey Bees (Microorganisms · 2024Article
- Unusual functions of insect vitellogenins: minireview.Physiological research · 2023Review
- Nosema apis and N. ceranae Infection in Honey bees: A Model for Host-Pathogen Interactions in Insects.Experientia supplementum (2012) · 2022Article
- Age and Season Effect the Timing of Adult Worker Honeybee Infection byFrontiers in cellular and infection microbiology · 2021Article
- Effects of Nosema ceranae (Dissociodihaplophasida: Nosematidae) and Flupyradifurone on Olfactory Learning in Honey Bees, Apis mellifera (Hymenoptera: Apidae).Journal of insect science (Online) · 2020Article
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Nosema ceranae is a pervasive and widespread honey bee pathogen that is associated with colony declines and has recently been shown to infect larval honey bees. In adult bees, Nosema infection is known to alter levels of a key protein, vitellogenin (Vg), which is necessary for egg-laying in queens, brood food production in workers, and proper immune function in all female bees. We therefore tested the effects of larval worker infection on hemolymph Vg titers. In 1-day old adult workers that were infected as larvae with 10,000 (10 K) or 40,000 (40 K) live N. ceranae spores/bee, Vg titers were significantly elevated by + 83% and + 73%, respectively, as compared to controls. At 7 days of adult age, Vg remained significantly elevated (+ 68%) in 10 K treated workers as compared to control workers. Nosema infection decreased total hemolymph protein titers in 1 and 7-day old adult bees (-50% in the 10 K and 40 K treated bees). Bees infected as larvae also had a more queen-like sting morphology. They developed slightly but significantly fewer barbs on their stings (-7% in the 40K-treated bees). Higher Vg levels are associated with younger bees. Thus, elevated Vg levels could delay normal age polyethism and disrupt colony balance.
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