Evidence map›Paper›PMID 29074994›Full record

ArticleScientific reports2017

Psychotropic in the environment: risperidone residues affect the behavior of fish larvae.

Fabiana Kalichak, Renan Idalencio, João Gabriel Santos da Rosa, Heloísa Helena de Alcântara Barcellos, Michele Fagundes, Angelo Piato, Leonardo José Gil Barcellos

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. End-of-life management strategies of pharmaceuticals in Portuguese households.Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA · 2023
    Review
  10. Article
  11. Article
  12. Waterborne agrichemicals compromise the anti-predatory behavior of zebrafish.Environmental science and pollution research international · 2020
    Article
  13. 17-α-Ethinylestradiol modulates endocrine and behavioral responses to stress in zebrafish.Environmental science and pollution research international · 2020
    Article
  14. Persistent and transgenerational effects of risperidone in zebrafish.Environmental science and pollution research international · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fabiana KalichakPrograma de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, Cidade Universitária, Camobi, Santa Maria, RS, 97105-900, Brazil.
Renan IdalencioPrograma de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, Cidade Universitária, Camobi, Santa Maria, RS, 97105-900, Brazil.
João Gabriel Santos da RosaPrograma de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, Cidade Universitária, Camobi, Santa Maria, RS, 97105-900, Brazil.
Heloísa Helena de Alcântara BarcellosPrograma de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, Cidade Universitária, Camobi, Santa Maria, RS, 97105-900, Brazil.
Michele FagundesUniversidade de Passo Fundo (UPF), BR 285, São José, Passo Fundo, RS, 99052-900, Brazil.
Angelo PiatoPrograma de Pós-Graduação em Farmacologia e Terapêutica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Sarmento Leite 500/305, Porto Alegre, RS, 90050-170, Brazil.ORCID 0000-0001-5109-7306
Leonardo José Gil BarcellosPrograma de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, Cidade Universitária, Camobi, Santa Maria, RS, 97105-900, Brazil. lbarcellos@upf.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to avoid and escape from predators are clearly relevant behaviors from the ecological perspective and directly interfere with the survival of organisms. Detected in the aquatic environment, risperidone can alter the behavior of exposed species. Considering the risk of exposure in the early stages of life, we exposed zebrafish embryos to risperidone during the first 5 days of life. Risperidone caused hyperactivity in exposed larvae, which in an environmental context, the animals may be more vulnerable to predation due to greater visibility or less perception of risk areas.

Indexed as

ZebrafishAnimalsBehavior, AnimalDose-Response Relationship, DrugDrug ResiduesLarvaPsychotropic DrugsRisperidoneWater Pollutants, ChemicalPsychotropic DrugsRisperidoneWater Pollutants, Chemical

Identifiers

PMID29074994
PMCPMC5658348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.