ArticleNature communications2017
Adaptive artificial evolution of droplet protocells in a 3D-printed fluidic chemorobotic platform with configurable environments.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Photo-Activated Merging Cascades in Droplet Swarms Upon Synergistic Solvation of Surfactants.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Article
- Robotic Modules for the Programmable Chemputation of Molecules and Materials.ACS central science · 2023Review
- Evolution of Proliferative Model Protocells Highly Responsive to the Environment.Life (Basel, Switzerland) · 2022Review
- Mostly 3D printed chemical synthesis robot.HardwareX · 2022Article
- Construction of Supramolecular Systems That Achieve Lifelike Functions.Materials (Basel, Switzerland) · 2022Review
- Proliferating coacervate droplets as the missing link between chemistry and biology in the origins of life.Nature communications · 2021Article
- Droplet Microfluidics for Tumor Drug-Related Studies and Programmable Artificial Cells.Global challenges (Hoboken, NJ) · 2021Review
- A curious formulation robot enables the discovery of a novel protocell behavior.Science advances · 2020Article
- Formation of Polarized, Functional Artificial Cells from Compartmentalized Droplet Networks and Nanomaterials, Using One-Step, Dual-Material 3D-Printed Microfluidics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Toward Experimental Evolution with Giant Vesicles.Life (Basel, Switzerland) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Evolution via natural selection is governed by the persistence and propagation of living things in an environment. The environment is important since it enabled life to emerge, and shapes evolution today. Although evolution has been widely studied in a variety of fields from biology to computer science, still little is known about the impact of environmental changes on an artificial chemical evolving system outside of computer simulations. Here we develop a fully automated 3D-printed chemorobotic fluidic system that is able to generate and select droplet protocells in real time while changing the surroundings where they undergo artificial evolution. The system is produced using rapid prototyping and explicitly introduces programmable environments as an experimental variable. Our results show that the environment not only acts as an active selector over the genotypes, but also enhances the capacity for individual genotypes to undergo adaptation in response to environmental pressures.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.