Evidence map›Paper›PMID 29074889›Full record

ArticleScientific reports2017

Unravelling pathways downstream Sox6 induction in K562 erythroid cells by proteomic analysis.

Gloria Barbarani, Antonella Ronchi, Margherita Ruoppolo, Lucia Santorelli, Robert Steinfelder, Sudharshan Elangovan, Cristina Fugazza, Marianna Caterino

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Gloria BarbaraniDipartimento di Biotecnologie e Bioscienze, Università degli studi di Milano-Bicocca, Milan, Italy.
Antonella RonchiDipartimento di Biotecnologie e Bioscienze, Università degli studi di Milano-Bicocca, Milan, Italy.
Margherita RuoppoloDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli, "Federico II", Naples, Italy.
Lucia SantorelliDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli, "Federico II", Naples, Italy.
Robert SteinfelderSource BioScience, Nottingham Business Park, Nottingham, United Kingdom.
Sudharshan ElangovanDipartimento di Biotecnologie e Bioscienze, Università degli studi di Milano-Bicocca, Milan, Italy.
Cristina FugazzaDipartimento di Biotecnologie e Bioscienze, Università degli studi di Milano-Bicocca, Milan, Italy. cristina.fugazza@unimib.it.
Marianna CaterinoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli, "Federico II", Naples, Italy. marianna.caterino@unina.it.
University of Milano-Bicocca · ITUniversity of Naples Federico II · ITCeinge Biotecnologie Avanzate (Italy) · ITSource BioScience (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Sox6 transcription factor is crucial for terminal maturation of definitive red blood cells. Sox6-null mouse fetuses present misshapen and nucleated erythrocytes, due to impaired actin assembly and cytoskeleton stability. These defects are accompanied with a reduced survival of Sox6

Indexed as

ProteomeErythroid CellsErythropoiesisGene ExpressionHEK293 CellsHumansK562 CellsProteomicsSOXD Transcription FactorsProteomeSOX6 protein, humanSOXD Transcription Factors

Identifiers

PMID29074889
PMCPMC5658338
OpenAlexW2765193773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.