Evidence map›Paper›PMID 29074778›Full record

ArticleScience (New York, N.Y.)2017

Obstruction of pilus retraction stimulates bacterial surface sensing.

Courtney K Ellison, Jingbo Kan, Rebecca S Dillard, David T Kysela, Adrien Ducret, Cecile Berne, Cheri M Hampton, Zunlong Ke, Elizabeth R Wright, Nicolas Biais and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 301 citations in OpenAlex.

  1. β-strand addition within tip initiation complexes licenses assembly of diverse type IV filaments.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Structural modeling reveals the mechanism of motor ATPase coordination during type IV pilus retraction.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. c-di-GMP-mediated pause behavior enablesApplied and environmental microbiology · 2026
    Article
  9. mBio · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Materials today. Bio · 2025
    Article
  20. Review

120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Courtney K EllisonDepartment of Biology, Indiana University, 1001 East 3rd Street, Bloomington, IN 47405, USA.ORCID 0000-0003-3259-079X
Jingbo KanBiology Department, CUNY Brooklyn College, 2900 Bedford Avenue, Brooklyn, NY 11210, USA.ORCID 0000-0003-2556-7073
Rebecca S DillardDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, 2015 Uppergate Drive, Atlanta, GA 30322, USA.
David T KyselaDepartment of Biology, Indiana University, 1001 East 3rd Street, Bloomington, IN 47405, USA.ORCID 0000-0001-7279-9198
Adrien DucretMolecular Microbiology and Structural Biochemistry, Université Lyon 1, CNRS, UMR 5086, 7 passage du Vercors, 69367 Lyon Cedex 07, France.ORCID 0000-0002-9076-405X
Cecile BerneDepartment of Biology, Indiana University, 1001 East 3rd Street, Bloomington, IN 47405, USA.ORCID 0000-0003-3731-9317
Cheri M HamptonDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, 2015 Uppergate Drive, Atlanta, GA 30322, USA.ORCID 0000-0003-0069-8712
Zunlong KeDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, 2015 Uppergate Drive, Atlanta, GA 30322, USA.ORCID 0000-0002-8408-850X
Elizabeth R WrightDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, 2015 Uppergate Drive, Atlanta, GA 30322, USA.ORCID 0000-0003-0712-9475
Nicolas BiaisBiology Department, CUNY Brooklyn College, 2900 Bedford Avenue, Brooklyn, NY 11210, USA.
Ankur B DaliaDepartment of Biology, Indiana University, 1001 East 3rd Street, Bloomington, IN 47405, USA.ORCID 0000-0003-2203-1230
Yves V BrunDepartment of Biology, Indiana University, 1001 East 3rd Street, Bloomington, IN 47405, USA. ybrun@indiana.edu.ORCID 0000-0002-9289-1909
Indiana University Bloomington · USChildren's Healthcare of Atlanta · USThe Graduate Center, CUNY · USGeorgia Institute of Technology · USUniversité Claude Bernard Lyon 1 · FR

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
GLOBAL CONTROL OF DIFFERENTIATION IN CAULOBACTERR01GM051986 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BRUN, YVES V · 1995 to 2016
$6.0M
Bacterial Subcellular Organization and its Impact on Growth, Development, Aging, and Surface AdhesionR35GM122556 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BRUN, YVES V · 2017 to 2019
$1.6M
Synthesis and properties of a bacterial bioadhesiveR01GM102841 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BRUN, YVES V · 2012 to 2015
$1.5M
Structure and Function of Prokaryotic Appendages by Cryo-Electron TomographyR01GM104540 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI WRIGHT, ELIZABETH R · 2013 to 2017
$1.4M
Mechanobiology of Neisseria MicrocoloniesSC2AI116566 · NIAID · BROOKLYN COLLEGE · PI BIAIS, NICOLAS · 2014 to 2016
$471k
Vibrio cholerae-chitin interactions and their role in cholera transmission and evolutionK22AI118863 · NIAID · TRUSTEES OF INDIANA UNIVERSITY · PI DALIA, ANKUR · 2016 to 2017
$268k
NIAID NIH HHS K22 AI118863NIAID NIH HHS P30 AI050409NIAID NIH HHS SC2 AI116566NIGMS NIH HHS R01 GM051986NIGMS NIH HHS R01 GM102841NIGMS NIH HHS R01 GM104540NIGMS NIH HHS R35 GM122556
6 · The paper itself

Abstract

It is critical for bacteria to recognize surface contact and initiate physiological changes required for surface-associated lifestyles. Ubiquitous microbial appendages called pili are involved in sensing surfaces and facilitating downstream behaviors, but the mechanism by which pili mediate surface sensing has been unclear. We visualized

Indexed as

Bacterial AdhesionCaulobacter crescentusFimbriae, BacterialFimbriae ProteinsFimbriae Proteins

Identifiers

PMID29074778
PMCPMC5805138
OpenAlexW2724541800

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.