Evidence map›Paper›PMID 29074704›Full record

ArticleThe Journal of experimental biology2017

Characterizing the distribution of steroid sulfatase during embryonic development: when and where might metabolites of maternal steroids be reactivated?

Ryan T Paitz, Kristin R Duffield, Rachel M Bowden

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of experimental biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ryan T PaitzSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA rpaitz@ilstu.edu.ORCID http://orcid.org/0000-0003-4609-4359
Kristin R DuffieldSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.
Rachel M BowdenSchool of Biological Sciences, Illinois State University, Normal, IL 61790, USA.ORCID http://orcid.org/0000-0002-9361-9659
Illinois State University · US

Funding

Characterizing the effect of bisphenol-A on the metabolism of maternally derivedR15ES023995 · NIEHS · ILLINOIS STATE UNIVERSITY · PI BOWDEN, RACHEL M · 2014 to 2014
$426k
NIEHS NIH HHS R15 ES023995
6 · The paper itself

Abstract

All vertebrate embryos are exposed to maternally derived steroids during development. In placental vertebrates, metabolism of maternal steroids by the placenta modulates embryonic exposure, but how exposure is regulated in oviparous vertebrates is less clear. Recent work in oviparous vertebrates has demonstrated that steroids are not static molecules, as they can be converted to more polar steroid sulfates by sulfotransferase enzymes. Importantly, these steroid sulfates can be converted back to the parent compound by the enzyme steroid sulfatase (STS). We investigated when and where STS was present during embryonic development in the red-eared slider turtle,

Indexed as

Embryonic DevelopmentAnimalsEmbryo, NonmammalianFemaleReptilian ProteinsSex FactorsSteroidsSteryl-SulfataseTemperatureTurtlesReptilian ProteinsSteroidsSteryl-SulfataseMaternal effectsOviparous vertebrateReptileSteroid metabolism

Identifiers

PMID29074704
PMCPMC5769565
OpenAlexW2766344462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.