Evidence map›Paper›PMID 29074633›Full record

ArticleAJNR. American journal of neuroradiology2017

Comparison between the Prebolus T1 Measurement and the Fixed T1 Value in Dynamic Contrast-Enhanced MR Imaging for the Differentiation of True Progression from Pseudoprogression in Glioblastoma Treated with Concurrent Radiation Therapy and Temozolomide Chemotherapy.

J G Nam, K M Kang, S H Choi, W H Lim, R-E Yoo, J-H Kim, T J Yun, C-H Sohn

Open access · hybridAbstract readComparative Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Evaluation of single bolus, dual-echo dynamic susceptibility contrast MRI protocols in brain tumor patients.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

J G NamFrom the Department of Radiology (J.G.N., K.M.K., S.H.C., W.H.L., R.-E.Y., J.-H.K., T.J.Y., C.-H.S.), Seoul National University Hospital, Seoul, Korea.ORCID http://orcid.org/0000-0003-3991-4523
K M KangFrom the Department of Radiology (J.G.N., K.M.K., S.H.C., W.H.L., R.-E.Y., J.-H.K., T.J.Y., C.-H.S.), Seoul National University Hospital, Seoul, Korea we3001@gmail.com.ORCID http://orcid.org/0000-0001-9643-2008
S H ChoiFrom the Department of Radiology (J.G.N., K.M.K., S.H.C., W.H.L., R.-E.Y., J.-H.K., T.J.Y., C.-H.S.), Seoul National University Hospital, Seoul, Korea.ORCID http://orcid.org/0000-0002-0412-2270
W H LimFrom the Department of Radiology (J.G.N., K.M.K., S.H.C., W.H.L., R.-E.Y., J.-H.K., T.J.Y., C.-H.S.), Seoul National University Hospital, Seoul, Korea.ORCID http://orcid.org/0000-0001-8985-8473
R-E YooFrom the Department of Radiology (J.G.N., K.M.K., S.H.C., W.H.L., R.-E.Y., J.-H.K., T.J.Y., C.-H.S.), Seoul National University Hospital, Seoul, Korea.ORCID http://orcid.org/0000-0002-5625-5921
J-H KimFrom the Department of Radiology (J.G.N., K.M.K., S.H.C., W.H.L., R.-E.Y., J.-H.K., T.J.Y., C.-H.S.), Seoul National University Hospital, Seoul, Korea.ORCID http://orcid.org/0000-0002-6349-6950
T J YunFrom the Department of Radiology (J.G.N., K.M.K., S.H.C., W.H.L., R.-E.Y., J.-H.K., T.J.Y., C.-H.S.), Seoul National University Hospital, Seoul, Korea.ORCID http://orcid.org/0000-0001-8441-4574
C-H SohnFrom the Department of Radiology (J.G.N., K.M.K., S.H.C., W.H.L., R.-E.Y., J.-H.K., T.J.Y., C.-H.S.), Seoul National University Hospital, Seoul, Korea.ORCID http://orcid.org/0000-0003-0039-5746
Seoul National University Hospital · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeGlioblastoma is the most common primary brain malignancy and differentiation of true progression from pseudoprogression is clinically important. Our purpose was to compare the diagnostic performance of dynamic contrast-enhanced pharmacokinetic parameters using the fixed T1 and measured T1 on differentiating true from pseudoprogression of glioblastoma after chemoradiation with temozolomide. MATERIALS AND

methodsThis retrospective study included 37 patients with histopathologically confirmed glioblastoma with new enhancing lesions after temozolomide chemoradiation defined as true progression (

resultsThe intraclass correlation coefficients of all the parameters from both T1 values were fair to excellent (0.689-0.999). The volume transfer constant and rate transfer constant from the fixed T1 were significantly higher in patients with true progression (

conclusionsThe dynamic contrast-enhanced parameter of rate transfer constant from the fixed T1 acted as a preferable marker to differentiate true progression from pseudoprogression.

Indexed as

AdultAgedAntineoplastic Agents, AlkylatingBrain NeoplasmsChemoradiotherapyContrast MediaDacarbazineDisease ProgressionFemaleGlioblastomaHumansMagnetic Resonance ImagingMaleMiddle AgedMultivariate AnalysisReproducibility of ResultsAntineoplastic Agents, AlkylatingContrast MediaDacarbazineTemozolomide

Identifiers

PMID29074633
PMCPMC7963756
OpenAlexW2765393847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.