Evidence map›Paper›PMID 29074576›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

A Presynaptic Function of Shank Protein in

Song Wu, Guangming Gan, Zhiping Zhang, Jie Sun, Qifu Wang, Zhongbao Gao, Meixiang Li, Shan Jin, Juan Huang, Ulrich Thomas and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Effect of Seminal Plasma on the Freezability of Boar Sperm.Animals : an open access journal from MDPI · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Song WuKey Laboratory for Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, University of Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0003-2926-5224
Guangming GanMedical School, Southeast University, Nanjing 210009, China.
Zhiping ZhangKey Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-0116-9719
Jie SunCollege of Life Science, Hubei University, Wuhan, Hubei 430062, China.ORCID 0000-0001-5210-6673
Qifu WangKey Laboratory for Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, University of Chinese Academy of Sciences, Beijing 100101, China.
Zhongbao GaoKey Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0003-2419-0948
Meixiang LiKey Laboratory for Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, University of Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0003-2406-516X
Shan JinCollege of Life Science, Hubei University, Wuhan, Hubei 430062, China.
Juan HuangSchool of Basic Medical Sciences, Nanjing Medical University, Nanjing 210029, China.ORCID 0000-0003-0915-4148
Ulrich ThomasLeibniz Institute for Neurobiology, Magdeburg 39118, Germany, and.ORCID 0000-0002-4372-8611
Yong-Hui JiangDepartments of Pediatrics and Neurobiology, Duke University School of Medicine, Durham, North Carolina 27710.
Yan LiKey Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-9431-6457
Rui TianKey Laboratory for Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, University of Chinese Academy of Sciences, Beijing 100101, China, rtian@gentics.ac.cn yqzhang@genetics.ac.cn.
Yong Q ZhangKey Laboratory for Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, University of Chinese Academy of Sciences, Beijing 100101, China, rtian@gentics.ac.cn yqzhang@genetics.ac.cn.ORCID 0000-0003-0581-4882
Institute of Genetics and Developmental Biology · CNChinese Academy of Sciences · CNHubei University · CNDuke University · USLeibniz Institute for Neurobiology · DENanjing Medical University · CNSoutheast University · CN

Funding

Analysis of Shank3 Complete and Temporal and Spatial Specific Knockout MiceR01MH098114 · NIMH · DUKE UNIVERSITY · PI JIANG, YONG-HUI · 2012 to 2016
$2.2M
A novel neural circuit analysis paradigm to model autism in miceR21MH104316 · NIMH · DUKE UNIVERSITY · PI JIANG, YONG-HUI · 2014 to 2015
$435k
A novel paradigm to dissect the function connectivity in Shank3 autism modelR21HD087795 · NICHD · YALE UNIVERSITY · PI JIANG, YONG-HUI · 2017 to 2018
$434k
NICHD NIH HHS R21 HD087795NIMH NIH HHS R01 MH098114NIMH NIH HHS R21 MH104316
6 · The paper itself

Abstract

Human genetic studies support that loss-of-function mutations in the

Indexed as

AnimalsAnimals, Genetically ModifiedDrosophilaFemaleMaleMushroom BodiesNerve Tissue ProteinsNeuromuscular JunctionPresynaptic TerminalsNerve Tissue ProteinsSHANK1 protein, humanSHANK2 protein, humanSHANK3 protein, humanautismmushroom body calyxPSDShanksynaptic function

Identifiers

PMID29074576
PMCPMC6705749
OpenAlexW2765946035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.