Evidence map›Paper›PMID 29074334›Full record

ArticleAcademic radiology2018

Robotically Assisted Long Bone Biopsy Under MRI Imaging: Workflow and Preclinical Study.

Kevin Cleary, Sunghwan Lim, Changhan Jun, Reza Monfaredi, Karun Sharma, Stanley Thomas Fricke, Luis Vargas, Doru Petrisor, Dan Stoianovici

Open access · greenAbstract read
In one paragraph

Article in Academic radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Low-Complexity Robotic Device for Magnetic Resonance Imaging-Guided Needle Biopsy.The international journal of medical robotics + computer assisted surgery : MRCAS · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. State of the Art and Future Opportunities in MRI-Guided Robot-Assisted Surgery and Interventions.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2022
    Article
  10. Article
  11. Robotically assisted long bone biopsy under MRI: cadaver study results.International journal of computer assisted radiology and surgery · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kevin ClearyChildren's National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, 111 Michigan Avenue, Washington, DC 20010. Electronic address: kcleary@childrensnational.org.
Sunghwan LimJohns Hopkins University, Brady Urological Institute, Urobotics Laboratory, Baltimore, Maryland.
Changhan JunJohns Hopkins University, Brady Urological Institute, Urobotics Laboratory, Baltimore, Maryland.
Reza MonfarediChildren's National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, 111 Michigan Avenue, Washington, DC 20010.
Karun SharmaChildren's National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, 111 Michigan Avenue, Washington, DC 20010.
Stanley Thomas FrickeChildren's National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, 111 Michigan Avenue, Washington, DC 20010.
Luis VargasChildren's National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, 111 Michigan Avenue, Washington, DC 20010.
Doru PetrisorJohns Hopkins University, Brady Urological Institute, Urobotics Laboratory, Baltimore, Maryland.
Dan StoianoviciJohns Hopkins University, Brady Urological Institute, Urobotics Laboratory, Baltimore, Maryland.
Children's National · USJohns Hopkins University · US

Funding

Pneumatic Robot for MRI-Guided Pediatrics Long Bone BiopsyR01CA172244 · NCI · CHILDREN'S RESEARCH INSTITUTE · PI CLEARY, KEVIN R., SZE, RAYMOND · 2013 to 2015
$1.6M
Robot-Assisted MRI-Guided Prostate BiopsyRC1EB010936 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI STOIANOVICI, DAN · 2009 to 2010
$979k
NCI NIH HHS R01 CA172244NHLBI NIH HHS HHSN268200900052CNIBIB NIH HHS RC1 EB010936
6 · The paper itself

Abstract

RATIONALE AND

objectivesOur research team has developed a magnetic resonance imaging (MRI)-compatible robot for long bone biopsy. The robot is intended to enable a new workflow for bone biopsy in pediatrics under MRI imaging. Our long-term objectives are to minimize trauma and eliminate radiation exposure when diagnosing children with bone cancers and bone infections. This article presents our robotic systems, phantom accuracy studies, and workflow analysis. MATERIALS AND

methodsThis section describes several aspects of our work including the envisioned clinical workflow, the MRI-compatible robot, and the experimental setup. The workflow consists of five steps and is intended to enable the entire procedure to be completed in the MRI suite. The MRI-compatible robot is MR Safe, has 3 degrees of freedom, and a remote center of motion mechanism for orienting a needle guide. The accuracy study was done in a Siemens Aera 1.5T scanner with a long bone phantom. Four targeting holes were drilled in the phantom.

resultsEach target was approached twice at slightly oblique angles using the robot needle guide for a total of eight attempts. A workflow analysis showed the average time for each targeting attempt was 32 minutes, including robot setup time. The average 3D targeting error was 1.39 mm with a standard deviation of 0.40 mm. All of the targets were successfully reached.

conclusionThe results showed the ability of the robotic system in assisting the radiologist to precisely target a bone phantom in the MRI environment. The robot system has several potential advantages for clinical application, including the ability to work at the MRI isocenter and serve as a steady and precise guide.

Indexed as

Magnetic Resonance ImagingRobotic Surgical ProceduresBone and BonesHumansImage-Guided BiopsyModels, BiologicalPhantoms, ImagingWorkflowlong bone biopsyMRIMR SafeRoboticsworkflow

Identifiers

PMID29074334
PMCPMC5723222
OpenAlexW2766362109

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.