Observational studyCritical care (London, England)2017
Functional evaluation of sublingual microcirculation indicates successful weaning from VA-ECMO in cardiogenic shock.
Observational study in Critical care (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07184476 (Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient), which is not on this map. Cited by 32 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient
Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Pooled it
- Parameters associated with successful weaning of veno-arterial extracorporeal membrane oxygenation: a systematic review.Critical care (London, England) · 2022Pooled it
- Understanding the "extracorporeal membrane oxygenation gap" in veno-arterial configuration for adult patients: Timing and causes of death.Artificial organs · 2021Pooled it
- Multiparameters associated to successful weaning from VA ECMO in adult patients with cardiogenic shock or cardiac arrest: Systematic review and meta-analysis.Annals of cardiac anaesthesiaPooled it
- Direct assessment of microcirculation in shock: a randomized-controlled multicenter study.Intensive care medicine · 2023Trial
- Beyond Blood Pressure: The Role of Flow Parameters and Biomarkers of Hypoperfusion in Cardiogenic Shock.Journal of clinical medicine · 2026Review
- Microcirculation and Cerebrovascular Autoregulation in Patients With Mechanical Circulatory Support Devices.Journal of stroke · 2026Review
- Comparison of Microcirculation in Chronic Heart Failure, Cardiogenic Shock, LVAD, and Heart Transplantation.JACC. Advances · 2026Article
- Beyond Standard Parameters: Precision Hemodynamic Monitoring in Patients on Veno-Arterial ECMO.Journal of personalized medicine · 2025Review
- Observational Study of Sublingual Microcirculation in Patients With Chronic Cardiovascular Disease.Microcirculation (New York, N.Y. : 1994) · 2025Observational
- Microcirculatory Changes in a Venous-Arterial Extracorporeal Membrane Oxygenation-Supported Patient with Cardiac Arrest Due to Aconitine Poisoning: A Case Report.Clinical medicine insights. Case reports · 2025Article
- Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) Support in New Era of Heart Transplant.Transplant international : official journal of the European Society for Organ Transplantation · 2024Review
- Overt disseminated intravascular coagulation and antithrombin III predict bleeding and in-hospital mortality in patients undergoing extracorporeal membrane oxygenation.Frontiers in medicine · 2024Article
- Advanced Perioperative Echocardiography in Venoarterial Extracorporeal Membrane Oxygenation Weaning Trial-Off.Texas Heart Institute journal · 2023Article
- Microcirculatory dysfunction in cardiogenic shock.Annals of intensive care · 2023Review
- Endothelial Damage and the Microcirculation in Critical Illness.Biomedicines · 2022Review
- Influence of Venoarterial Extracorporeal Membrane Oxygenation Integrated Hemoadsorption on the Early Reversal of Multiorgan and Microcirculatory Dysfunction and Outcome of Refractory Cardiogenic Shock.Journal of clinical medicine · 2022Article
- Predictors of weaning failure in case of VA ECMO implantation.Scientific reports · 2022Article
- Hemodynamic-based Assessment and Management of Cardiogenic Shock.US cardiology · 2022Review
- Case Report: Early Identification of Subclinical Cardiac Tamponade in a Patient With a Left Ventricular Assist Device by the Use of Sublingual Microcirculatory Imaging: A New Diagnostic Imaging Tool?Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVeno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly adopted for the treatment of cardiogenic shock (CS). However, a marker of successful weaning remains largely unknown. Our hypothesis was that successful weaning is associated with sustained microcirculatory function during ECMO flow reduction. Therefore, we sought to test the usefulness of microcirculatory imaging in the same sublingual spot, using incident dark field (IDF) imaging in assessing successful weaning from VA-ECMO and compare IDF imaging with echocardiographic parameters.
methodsWeaning was performed by decreasing the VA-ECMO flow to 50% (F
resultsPatients (n = 13) aged 49 ± 18 years, who received VA-ECMO for the treatment of refractory CS due to pulmonary embolism (n = 5), post cardiotomy (n = 3), acute coronary syndrome (n = 2), myocarditis (n = 2) and drug intoxication (n = 1), were included. TVDss
conclusionThis study identified sublingual microcirculation as a novel potential marker for identifying successful weaning from VA-ECMO. Sustained values of TVDss
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.