Trial reportHead & face medicine2017
Clinical and radiographic evaluation of pulpectomy in primary teeth: a 18-months clinical randomized controlled trial.
Trial report in Head & face medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05448937 (Clinical And Radiographic Evaluation Of Lesion Sterilization And Tissue Repair Versus Zinc Oxide And Eugenol For Treatment of Necrotic Primary Molars), which is not on this map. Cited by 38 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical And Radiographic Evaluation Of Lesion Sterilization And Tissue Repair Versus Zinc Oxide And Eugenol For Treatment of Necrotic Primary Molars
Who cites it
38 citing papers in PubMed, 6 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Evaluation of oral health-related quality of life following pulp therapy or extraction in paediatric patients: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Different outcomes of rotary and manual instrumentation in primary teeth pulpectomy: a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Pooled it
- Conventional methods and electronic apical locator in determining working length in different primary teeth: systematic review and meta-analysis of clinical studies.Evidence-based dentistry · 2025Pooled it
- Alternative root canal filling materials to zinc oxide eugenol in primary teeth: a systematic review of the literature.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023Pooled it
- A comparison of calcium hydroxide/iodoform paste and zinc oxide eugenol as root filling materials for pulpectomy in primary teeth: A systematic review and meta-analysis.Clinical and experimental dental research · 2019Pooled it
- The Clinical Effectiveness of Calcium Hydroxide in Root Canal Disinfection of Primary Teeth: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2019Pooled it
- Clinical and radiographic outcomes of pulpectomy in primary teeth using two rotary file systems compared with manual files: a cost-effectiveness analysis.BMC oral health · 2025Trial
- Pulpotomy versus pulpectomy in carious vital pulp exposure in primary incisors: a randomized controlled trial.BMC oral health · 2024Trial
- Evaluation of the removal ability of Iodoform Paste in primary teeth pulpectomies using rotary files: a pilot study.Scientific reports · 2026Article
- Modifications of Resorbable Root Canal Filling Materials for Primary Teeth: A Systematic Review.Materials (Basel, Switzerland) · 2026Review
- Clinical and Radiographic Evaluation of Photodynamic Therapy in Root Canal Treatment of Primary Molars: A 15-month Randomized Clinical Trial.International journal of clinical pediatric dentistry · 2026Article
- Pulpotomy vs. pulpectomy for equivocal pulp status in primary molars: a retrospective cohort study with propensity score matching.BMC oral health · 2026Article
- Assessment of Alterations in Permanent Premolars After Endodontic Treatment of Predecessor Primary Molars: A Prospective Study.International journal of paediatric dentistry · 2026Article
- Factors Affecting Success and Failure of Pulpectomy in Primary Teeth: A Systematic Review.International journal of clinical pediatric dentistry · 2025Article
- [Antibacterial properties, biocompatibility, and clinical selection strategies of root canal filling materials for primary teeth].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Review
- Evaluation of the shaping effectiveness of three different rotary systems and hand files in primary molars: a micro-CT in vitro study.BMC oral health · 2025Article
- Pulpectomy in a Primary Second Molar With a Questionable Prognosis and Extruded Obturation Material.Cureus · 2025Article
- Survival analysis of primary molars following pulpectomy performed under dental general anesthesia: a five-year retrospective study.BMC oral health · 2024Article
- The Antibacterial Properties of a Reinforced Zinc Oxide Eugenol Combined with Cloisite 5A Nanoclay: An In-Vitro Study.Journal of functional biomaterials · 2024Article
- Dental treatment outcomes in Thai children treated for severe early-childhood caries under general anaesthesia and non-pharmacological behaviour management: a retrospective study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo avoid untoward changes when primary teeth are replaced by permanent teeth, resorption of the material used in primary teeth root canal filling should occur at the same rate as root resorption. The Aim of this study was to compare the success rates of a mixed primary root canal filling (MPRCF, ingredients: zinc oxide-eugenol [ZOE], iodoform, calcium hydroxide) to those of ZOE and Vitapex in pulpectomised primary molars.
methodsOne hundred and sixty primary molars from 155 children (average age 5.88 ± 1.27 years) underwent two-visit pulpectomy using one of the three materials. The clinical and radiographic findings at 6, 12 and 18 months were assessed.
resultsAt 6 and 12 months, the MPRCF and ZOE success rates were 100%. The Vitapex group showed clinical success rate and radiographic success rate of 100 and 94.5% at 6 months, and 80.4 and 60.7% at 12 months. The 18-month clinical success rates of the MPRCF, ZOE and Vitapex were 96.2, 92.2 and 71.4% and radiographic success rates were 92.5, 88.2 and 53.6%, respectively. There was a statistically significant difference in the success rates between MPRCF and Vitapex and no significant differences between MPRCF and ZOE. More MPRCF were resorbed at same rate with roots than ZOE and Vitapex. Early resorption of root filling resulted in more failure.
conclusionsThe mixture of ZOE, iodoform and calcium hydroxide can be considered an effective root canal filling material in pulp involved primary teeth and had no adverse effect on tooth replacement.
trial registrationChiCTR-TRC-14004938 . Registered 13 July 2014.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.