Evidence map›Paper›PMID 29073808›Full record

ArticleMolecular imaging

Whole-Body Biodistribution, Dosimetry, and Metabolite Correction of [

Nana L Christensen, Steen Jakobsen, Anna C Schacht, Ole L Munk, Aage K O Alstrup, Lars P Tolbod, Hendrik J Harms, Søren Nielsen, Lars C Gormsen

Open access · goldAbstract read
In one paragraph

Article in Molecular imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. An improved fully-automated GMP radiosynthesis of [EJNMMI radiopharmacy and chemistry · 2026
    Article
  3. Can Nuclear Imaging Detect Trained Immunity in Cardiovascular Disease?Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Heart Uptake of [Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Novel Tracers and Radionuclides in PET Imaging.Radiologic clinics of North America · 2021
    Review
  15. A hyperspectral approach for recovering agent excretion biodistributions using whole-body fluorescence cryo-imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2021
    Article
  16. Article
  17. Clinical translation ofEuropean journal of nuclear medicine and molecular imaging · 2020
    Article
  18. Article
  19. Quantitative PET of liver functions.American journal of nuclear medicine and molecular imaging · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Nana L Christensen1 Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus C, Denmark.
Steen Jakobsen1 Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus C, Denmark.
Anna C Schacht1 Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus C, Denmark.
Ole L Munk1 Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus C, Denmark.
Aage K O Alstrup1 Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus C, Denmark.
Lars P Tolbod1 Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus C, Denmark.
Hendrik J Harms1 Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus C, Denmark.
Søren Nielsen2 Department of Endocrinology, Aarhus University Hospital, Aarhus C, Denmark.
Lars C Gormsen1 Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus C, Denmark.
Aarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite the decades long use of [

methodsDosimetry and biodistribution studies were performed in 2 pigs and 2 healthy volunteers by whole-body [

resultsIn humans, mean effective dose was 3.23 (0.02) µSv/MBq, with the liver and myocardium receiving the highest absorbed doses. Metabolite correction using only [

conclusionFirst, mean effective dose of [

Indexed as

MetabolomePositron-Emission TomographyRadiometryAnimalsCarbon RadioisotopesFemaleHumansImage Processing, Computer-AssistedKineticsMaleMiddle AgedPalmitatesRadiopharmaceuticalsSolid Phase ExtractionSus scrofaTissue DistributionCarbon-11Carbon RadioisotopesPalmitatesRadiopharmaceuticalsadvances in PET/SPECT probescardiac imagingmetabolismPET/CTquantitation in molecular imaging

Identifiers

PMID29073808
PMCPMC5665104
OpenAlexW2765515383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.