ArticleJournal of critical care2018
Low tidal volume ventilation use remains low in patients with acute respiratory distress syndrome at a single center.
Article in Journal of critical care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Delivery of Lung-protective Ventilation for Acute Respiratory Distress Syndrome: A Hybrid Implementation-Effectiveness Trial.Annals of the American Thoracic Society · 2023Trial
- Effect of Positive End-Expiratory Pressure (PEEP) Titration in Elderly Patients Undergoing Lobectomy.Medical science monitor : international medical journal of experimental and clinical research · 2022Trial
- Bench evidence, bedside uncertainty: hyperoxia, mechanical ventilation and lung injury.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Optimizing Mechanical Ventilation Strategies in ARDS: The Role of Driving Pressure and Low Tidal Volume Ventilation.Critical care research and practice · 2025Review
- Low-Frequency Ventilation May Facilitate Weaning in Acute Respiratory Distress Syndrome Treated with Extracorporeal Membrane Oxygenation: A Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Assessing Evidence-Based Practice Knowledge, Self-Efficacy, and Use Among Respiratory Therapists.Respiratory care · 2024Article
- Intermediate tidal volume is an acceptable option for ventilated patients with acute respiratory distress syndrome.Medicina intensiva · 2022Article
- Intermediate tidal volume is an acceptable option for ventilated patients with acute respiratory distress syndrome.Medicina intensiva · 2022Article
- Low tidal volume ventilation is associated with mortality in COVID-19 patients-Insights from the PRoVENT-COVID study.Journal of critical care · 2022Observational
- Simulation-based Assessment to Measure Proficiency in Mechanical Ventilation among Residents.ATS scholar · 2022Article
- The first step is recognizing there is a problem: a methodology for adjusting for variability in disease severity when estimating clinician performance.BMC medical research methodology · 2022Article
- Use of a Portable Electronic Interface Improves Clinical Handoffs and Adherence to Lung Protective Ventilation.Medical devices (Auckland, N.Z.) · 2022Article
- Promoting Evidence-Based Practice in Acute Respiratory Distress Syndrome: A Systematic Review.Critical care explorations · 2021Review
- Early adoption of critical care interventions is unjustifiable without concomitant effectiveness study.Critical care (London, England) · 2020Article
- Clinician Recognition of the Acute Respiratory Distress Syndrome: Risk Factors for Under-Recognition and Trends Over Time.Critical care medicine · 2020Article
- Fluid management in ARDS: an evaluation of current practice and the association between early diuretic use and hospital mortality.Journal of intensive care · 2020Article
- Mechanical Ventilation Training During Graduate Medical Education: Perspectives and Review of the Literature.Journal of graduate medical education · 2019Review
- Article
- Impact of a respiratory ICU rotation on resident knowledge and confidence in managing mechanical ventilation.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposeLow tidal volume ventilation (LTVV) reduces mortality in acute respiratory distress syndrome (ARDS) patients. Understanding local barriers to LTVV use at a former ARDS Network hospital may provide new insight to improve LTVV implementation.
methodsA cohort of 214 randomly selected adults met the Berlin definition of ARDS at Harborview Medical Center between 2008 and 2012. The primary outcome was the receipt of LTVV (tidal volume of ≤6.5mL/kg predicted body weight) within 48h of ARDS onset. We constructed a multivariable logistic regression model to identify factors associated with the outcome.
resultsOnly 27% of patients received tidal volumes of ≤6.5mL/kg PBW within 48h of ARDS onset. Increasing plateau pressure (OR 1.11; 95% CI 1.03 to 1.19; p-value<0.01) was positively associated with LTVV use while increasing PaO
conclusionsMost ARDS patients did not receive LTVV despite implementation of a protocol. ARDS was also recognized in a minority of patients, suggesting an opportunity for improvement of care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.