Evidence map›Paper›PMID 29073519›Full record

ArticleBiosensors & bioelectronics2018

Re-usable electrochemical glucose sensors integrated into a smartphone platform.

Amay J Bandodkar, Somayeh Imani, Rogelio Nuñez-Flores, Rajan Kumar, Chiyi Wang, A M Vinu Mohan, Joseph Wang, Patrick P Mercier

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors & bioelectronics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Nanomaterials-based sensors for the detection of COVID-19: A review.Bioengineering & translational medicine · 2022
    Review
  5. Article
  6. Biomarkers and Detection Platforms for Human Health and Performance Monitoring: A Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Biosensors in Occupational Safety and Health Management: A Narrative Review.International journal of environmental research and public health · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amay J BandodkarDepartment of Nanoengineering, University of California, San Diego, La Jolla, CA, USA.
Somayeh ImaniDepartment of Electrical & Computer Engineering, University of California, San Diego, La Jolla, CA, USA.
Rogelio Nuñez-FloresDepartment of Nanoengineering, University of California, San Diego, La Jolla, CA, USA.
Rajan KumarDepartment of Nanoengineering, University of California, San Diego, La Jolla, CA, USA.
Chiyi WangDepartment of Electrical & Computer Engineering, University of California, San Diego, La Jolla, CA, USA.
A M Vinu MohanDepartment of Nanoengineering, University of California, San Diego, La Jolla, CA, USA.
Joseph WangDepartment of Nanoengineering, University of California, San Diego, La Jolla, CA, USA. Electronic address: josephwang@ucsd.edu.
Patrick P MercierDepartment of Electrical & Computer Engineering, University of California, San Diego, La Jolla, CA, USA. Electronic address: pmercier@ucsd.edu.

Funding

A Flexible Epidermal Multimodal Health MonitorR21EB019698 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MERCIER, PATRICK P · 2015 to 2016
$395k
NIBIB NIH HHS R21 EB019698
6 · The paper itself

Abstract

This article demonstrates a new smartphone-based reusable glucose meter. The glucose meter includes a custom-built smartphone case that houses a permanent bare sensor strip, a stylus that is loaded with enzyme-carbon composite pellets, and sensor instrumentation circuits. A custom-designed Android-based software application was developed to enable easy and clear display of measured glucose concentration. A typical test involves the user loading the software, using the stylus to dispense an enzymatic pellet on top of the bare sensor strip affixed to the case, and then introducing the sample. The electronic module then acquires and wirelessly transmits the data to the application software to be displayed on the screen. The deployed pellet is then discarded to regain the fresh bare sensor surface. Such a unique working principle allows the system to overcome challenges faced by previously reported reusable sensors, such as enzyme degradation, leaching, and hysteresis effects. Studies reveal that the enzyme loaded in the pellets are stable for up to 8 months at ambient conditions, and generate reproducible sensor signals. The work illustrates the significance of the pellet-based sensing system towards realizing a reusable, point-of-care sensor that snugly fits around a smartphone and which does not face issues usually common to reusable sensors. The versatility of this system allows it to be easily modified to detect other analytes for application in a wide range of healthcare, environmental and defense domains.

Indexed as

Biosensing TechniquesBlood GlucoseElectrochemical TechniquesElectrodesEquipment DesignHumansPoint-of-Care SystemsReproducibility of ResultsSmartphoneBlood GlucoseElectrochemical biosensorsGlucometerGlucoseSmartphone

Identifiers

PMID29073519
PMCPMC5841915

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.