ArticleJournal of dental research2018
Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging.
Article in Journal of dental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- USP34 attenuates cartilage degradation in temporomandibular joint osteoarthritis by ANT1-mediated mitophagy.JBMR plus · 2026Article
- Exploring the Cellular and Molecular Mechanism of Discoidin Domain Receptors (DDR1 and DDR2) in Bone Formation, Regeneration, and Its Associated Disease Conditions.International journal of molecular sciences · 2023Review
- Discoidin domain receptors; an ancient family of collagen receptors has major roles in bone development, regeneration and metabolism.Frontiers in dental medicine · 2023Article
- Temporomandibular Joint Osteoarthritis: Pathogenic Mechanisms Involving the Cartilage and Subchondral Bone, and Potential Therapeutic Strategies for Joint Regeneration.International journal of molecular sciences · 2022Review
- Animal Models of Temporomandibular Joint Osteoarthritis: Classification and Selection.Frontiers in physiology · 2022Review
- Role of Discoidin Domain Receptor 2 in Craniofacial Bone Regeneration.Journal of dental research · 2021Article
- Pathological mechanism of chondrocytes and the surrounding environment during osteoarthritis of temporomandibular joint.Journal of cellular and molecular medicine · 2021Review
- Role of Runx2 in prostate development and stem cell function.The Prostate · 2021Article
- The Role of Discoidin Domain Receptor 2 in Tooth Development.Journal of dental research · 2020Article
- Loss of Discoidin Domain Receptor 1 Predisposes Mice to Periodontal Breakdown.Journal of dental research · 2019Article
- Modulation of biomimetic mineralization of collagen by soluble ectodomain of discoidin domain receptor 2.Materials science & engineering. C, Materials for biological applications · 2019Article
- Part II: Temporomandibular Joint (TMJ)-Regeneration, Degeneration, and Adaptation.Current osteoporosis reports · 2018Review
- Cell-Matrix Interactions and Matricrine Signaling in the Pathogenesis of Vascular Calcification.Frontiers in cardiovascular medicine · 2018Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Temporomandibular joint (TMJ) disorders are often associated with development of osteoarthritis-like changes in the mandibular condyle. Discoidin domain receptor 2 (DDR2), a collagen receptor preferentially activated by type I and III collagen found in the TMJ and other fibrocartilages, has been associated with TMJ degeneration, but its role in normal joint development has not been previously examined. Using Ddr2 LacZ-tagged mice and immunohistochemistry, we found that DDR2 is preferentially expressed and activated in the articular zone of TMJs but not knee joints. To assess the requirement for Ddr2 in TMJ development, studies were undertaken to compare wild-type and smallie ( slie) mice, which contain a spontaneous deletion in Ddr2 to produce an effective null allele. Analysis of TMJs from newborn Ddr2
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.