Evidence map›Paper›PMID 29073200›Full record

Trial reportPloS one2017

Torsional phacoemulsification: A pilot study to revise the "harm scale" evaluating the endothelial damage and the visual acuity after cataract surgery.

Francesco Saverio Sorrentino, Silvia Matteini, Aurelio Imburgia, Claudio Bonifazzi, Adolfo Sebastiani, Francesco Parmeggiani

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Francesco Saverio SorrentinoDepartment of Surgical Sciences, Unit of Ophthalmology, Ospedale Maggiore, Bologna, Italy.ORCID http://orcid.org/0000-0002-7691-8980
Silvia MatteiniDepartment of Biomedical and Surgical Sciences, Division of Ophthalmology, University of Ferrara, Ferrara, Italy.
Aurelio ImburgiaDepartment of Surgical Sciences, Unit of Ophthalmology, Ospedale di San Marino, San Marino, Repubblica di San Marino.
Claudio BonifazziDepartment of Biomedical and Surgical Sciences, Section of Human Physiology, University of Ferrara, Ferrara, Italy.
Adolfo SebastianiClinic of Ophthalmology, University of Ferrara, Ferrara, Italy.
Francesco ParmeggianiDepartment of Biomedical and Surgical Sciences, Division of Ophthalmology, University of Ferrara, Ferrara, Italy.
University of Ferrara · ITOspedale di Stato della Repubblica di San Marino · SMOspedale Maggiore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the effect of torsional phacoemulsification energy on corneal endothelium evaluating the relationship between changes of endothelial cells and postoperative visual acuity.

methodsThis prospective clinical observational cohort study included 50 patients with cataract who underwent torsional phacoemulsification. Sequential quantitative and qualitative morphometric endothelial cell analyses of the cornea were performed four weeks preoperatively and six weeks postoperatively using noncontact specular microscopy.

resultsThis work confirmed the strong relationship, described by a linear model (one-way ANOVA, R2 = 77.9%, P < 0.0001), between the percentage of endothelial cell loss (ECL%) and the 5-score harm scale. According to the Tukey post-hoc pairwise comparison test, distinct values of ECL% are grouped in 3 subsets. The value of ECL = 10% has been identified as cut-off to discriminate patients with excellent postoperative best-corrected visual acuity (BCVA > 85 letters) from those with just a good/satisfied visual outcome (BCVA ≤ 85 letters). Within the 5-score harm scale, there was a significant correlation among phaco energy intraoperatively delivered and the average endothelial cell loss.

conclusionsThis study confirms the validity of the 5-score harm scale first proposed by Sorrentino and colleagues in 2016. This time, the method categorizes cataracts taking into account nucleus hardness and phaco cumulative dissipated energy. Predicting the harm on corneal endothelium, we can discriminate patients with excellent BCVA and with just good/satisfied BCVA. With torsional phacoemulsification with respect to longitudinal, the percentage of patients who can reach excellent BCVA is remarkably increased.

Indexed as

Visual AcuityEndothelium, CornealFemaleHumansMaleMiddle AgedPhacoemulsificationPilot ProjectsProspective Studies

Identifiers

PMID29073200
PMCPMC5658130
OpenAlexW2766942221

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.