ArticlePloS one2017
Etiology and mode of presentation of chronic liver diseases in India: A multi centric study.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 131 citations in OpenAlex.
- A randomized controlled trial of L-taurine for fatigue in decompensated cirrhosis.Hepatology communications · 2026Trial
- Randomised clinical trial: effect of adding branched chain amino acids to exercise and standard-of-care on muscle mass in cirrhotic patients with sarcopenia.Hepatology international · 2022Trial
- Effect of long-term aggressive nutrition therapy on survival in patients with alcohol-related cirrhosis: A randomized controlled trial.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022Trial
- Renal Dysfunction Across Etiologies of Chronic Liver Disease: A Cross-Sectional Study From a Tertiary Care Center.Cureus · 2026Article
- Correlation of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio with serum-ascites albumin gradient in ascites.Bioinformation · 2026Article
- Toxins to treatments: Impact of environmental pollutants, gut microbiota, and natural compounds on non-alcoholic fatty liver disease progression.World journal of hepatology · 2025Review
- Magnitude and factors associated with chronic liver disease among adults (≥ 18 Years) attending gastroenterology and hepatology clinics in selected public hospitals, West Arsi Zone, Ethiopia: a cross-sectional study.BMC public health · 2025Article
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- Epidemiological trends and projections to 2035 of hepatitis B burden in China, 1990-2021.PloS one · 2025Article
- Seroprevalence and Predictors of Hepatitis B and C Virus Infections Among Patients with Chronic Liver Diseases in Dodoma Region, Tanzania: A Cross-Sectional Study.Hepatic medicine : evidence and research · 2025Article
- Distribution of Normative Percentiles of Liver Stiffness Measurement Using Ultrasound Shear Wave Elastography in an Adult Asian Indian Population.The Indian journal of radiology & imaging · 2024Article
- Serum zinc level in liver cirrhosis with hepatic encephalopathy and its correlation with different stages of hepatic encephalopathy.Journal of family medicine and primary care · 2024Article
- Article
- Clinical and laboratory parameters as predictors of mortality in patients with chronic liver disease presenting to emergency department- a cross sectional study.International journal of emergency medicine · 2024Article
- The Use ofBiomedicines · 2024Review
- Outcome of individuals with alcoholic cirrhosis hospitalized with first decompensation and their predictors.The Indian journal of medical research · 2024Article
- Article
- Portal Vein Thrombosis in Patients With Cirrhosis of the Liver: Prevalence and Risk Factors.Cureus · 2023Article
- Global epidemiology of cirrhosis - aetiology, trends and predictions.Nature reviews. Gastroenterology & hepatology · 2023Review
- Association of Thyroid Function and Severity of Illness in Liver Cirrhosis as Measured by Child-Pugh Score.Cureus · 2023Article
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Authors and funding
15 authors at 11 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a paucity of health policy relevant data for chronic liver disease from India, impeding formulation of an interventional strategy to address the issue. A prospective, multicentric study to delineate the etiology and clinical profile of chronic liver disease in India is reported here. A centrally coordinated and monitored web-based data repository was developed (Feb, 2010 to Jan, 2013) and analyzed. Eleven hospitals from different parts of India participated. Data were uploaded into a web based proforma and monitored by a single centre according to a standardized protocol. 1.28% (n = 266621) of all patients (n = 20701383) attending the eleven participating hospitals of India had liver disease. 65807 (24·68%) were diagnosed for the first time (new cases). Of these, 13014 (19·77%, median age 43 years, 73% males) cases of chronic liver disease were finally analyzed. 33.9% presented with decompensated cirrhosis. Alcoholism (34·3% of 4413) was the commonest cause of cirrhosis while Hepatitis B (33·3%) was predominant cause of chronic liver disease in general and non-cirrhotic chronic liver disease (40·8% out of 8163). There was significant interregional differences (hepatitis C in North, hepatitis B in East and South, alcohol in North-east, Non-alcoholic Fatty Liver Disease in West) in the predominant cause of chronic liver disease. Hepatitis B (46·8% of 438 cases) was the commonest cause of hepatocellular Cancer.11·7% had diabetes. Observations of our study will help guide a contextually relevant liver care policy for India and could serve as a framework for similar endeavor in other developing countries as well.
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