Evidence map›Paper›PMID 29073175›Full record

ArticlePloS one2017

Dissociation between behavior and motor cortical excitability before and during ballistic wrist flexion and extension in young and old adults.

Tibor Hortobágyi, Adinda Mieras, John Rothwell, Miguel Fernandez Del Olmo

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Motor Cortex Excitability Reflects the Subjective Value of Reward and Mediates Its Effects on Incentive-Motivated Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Tibor HortobágyiUniversity of Groningen, University of Groningen Medical Center, Center for Human Movement Sciences, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-5731-6423
Adinda MierasUniversity of Groningen, University of Groningen Medical Center, Center for Human Movement Sciences, Groningen, The Netherlands.
John RothwellInstitute of Neurology, University College, London, United Kingdom.
Miguel Fernandez Del OlmoLearning and Human Movement Control Group, University of A Coruña, A Coruña, Spain.
University Medical Center Groningen · NLUniversidade da Coruña · ESUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAging is associated with slow reactive movement generation and poor termination.

objectiveWe examined the hypothesis that the build-up of excitability in the primary motor cortex in the agonist muscle to generate ballistic wrist flexion and extension and in the antagonist to stop the movement, is lower and slower in old compared with young adults.

methodsWe measured the size of the motor potentials evoked (MEP) produced by transcranial magnetic stimulation (TMS), background integrated EMG (iEMG), and the MEP:iEMG ratio in healthy young (23 y, n = 14) and old adults' (73 y, n = 14) wrist flexors and extensors as they rapidly flexed or extended the wrist in response to an auditory cue. TMS was delivered at 80% of resting motor threshold randomly in 20 ms increments between 130 and 430 ms after the tone.

resultsEven though old compared to young adults executed the two wrist movements with ~23% longer movement duration and ~15% longer reaction time (both p < 0.05), the rise in MEP:iEMG ratio before the main similar in the two age groups.

conclusionThese data suggest that an adjustment of current models might be needed to better understand how and if age affects the build-up excitability accompanying movement generation and termination.

Indexed as

Range of Motion, ArticularAdultAgedElectromyographyEvoked Potentials, MotorFemaleHumansMaleTranscranial Magnetic StimulationWristYoung Adult

Identifiers

PMID29073175
PMCPMC5658056
OpenAlexW2767046163

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.