ArticleProceedings of the National Academy of Sciences of the United States of America2017
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Open access · bronzeAbstract read
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 57 citations in OpenAlex.
- Precision Aptamers Against a Native GPCR through Ligand-Guided Selection.bioRxiv : the preprint server for biology · 2026Article
- Qualitative beta-2-adrenoceptor signaling in the regulation of human airway epithelia mucin and cytokine production.Respiratory research · 2026Article
- Light-Based Molecular Tools to Precisely Monitor and Operate β-Adrenoceptors.Medicinal research reviews · 2026Review
- Potential mechanisms and effects of AFB1-induced asthma: A comprehensive analysis based on network toxicology and molecular docking.PloS one · 2026Article
- Epigenomic study of the lower airway reveals COPD-associated methylation patterns and potential microbiota links.BMJ open respiratory research · 2025Article
- Biased Orthosteric Agonism and Allosteric Modulation: Emerging Strategies for Developing New Class of β-Agonists for Obstructive Airway Diseases.American journal of respiratory cell and molecular biology · 2025Review
- Airway sympathectomy attenuates inflammation, transcriptional ratios of Muc5ac and Muc5b, and airway mechanic deficits in mice delivered intranasal IL-13.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Sex-dependent influence of LMAN1 on allergen-induced airway hyperresponsiveness.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- β-arrestin2: an emerging player and potential therapeutic target in inflammatory immune diseases.Acta pharmacologica Sinica · 2025Review
- GRespiratory research · 2024Review
- The Wiser Strategy of Using Beta-Agonists in Asthma: Mechanisms and Rationales.Allergy, asthma & immunology research · 2024Review
- Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists.Communications biology · 2024Article
- Regional variations in allergen-induced airway inflammation correspond to changes in soluble guanylyl cyclase heme and expression of heme oxygenase-1.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Structures of Adrenoceptors.Handbook of experimental pharmacology · 2024Review
- β-adrenergic receptor regulates embryonic epithelial extensibility through actomyosin inhibition.iScience · 2023Article
- Therapeutic Targets and Precision Medicine in COPD: Inflammation, Ion Channels, Both, or Neither?International journal of molecular sciences · 2023Review
- Differential Roles of Interleukin-6 in Severe Acute Respiratory Syndrome-Coronavirus-2 Infection and Cardiometabolic Diseases.Cardiology discovery · 2023Article
- Bronchial epithelial and airway smooth muscle cell interactions in health and disease.Heliyon · 2023Review
- Inhibition of TRPA1, Endoplasmic Reticulum Stress, Human Airway Epithelial Cell Damage, and EctopicPharmaceuticals (Basel, Switzerland) · 2023Article
- Exploration and Validation of Potential Biomarkers and Therapeutic Targets in Ferroptosis of Asthma.Journal of asthma and allergy · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 2 countries.
Long P NguyenDepartment of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Nour A Al-SawalhaDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, TX 77004.
Sergio ParraDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, TX 77004.
Indira PokkunuriDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, TX 77004.
Ozozoma OmoluabiDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77004.
Adedoyin A OkulateDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, TX 77004.
Elizabeth Windham LiDepartment of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Matthew HazenDepartment of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Jose M Gonzalez-GranadoSchool of Life Sciences, College of Medical, Veterinary and Life Science, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
Craig J DalySchool of Life Sciences, College of Medical, Veterinary and Life Science, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
John C McGrathSchool of Life Sciences, College of Medical, Veterinary and Life Science, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
Michael J TuvimDepartment of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Brian J KnollDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, TX 77004.
Burton F DickeyDepartment of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Richard A BondDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, TX 77004; rabond@uh.edu.
University of Houston · USThe University of Texas MD Anderson Cancer Center · USUniversity of Glasgow · GB
Funding
Immunology Scientist Training ProgramT32AI053831 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI CORRY, DAVID B · 2003 to 2018
$4.2MControlling the core airway mucin secretion machinery to prevent pathophysiologyR01HL129795 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DICKEY, BURTON F · 2015 to 2023
$3.8MOptimizing Beta-Adrenoceptor Signaling Bias in AsthmaR01AI110007 · NIAID · DUKE UNIVERSITY · PI BOND, RICHARD AGUSTIN, PENN, RAYMOND B. · 2014 to 2018
$3.2MMolecular Pathways Regulating Airway Goblet Cell Mucin SecretionR01HL097000 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVIS, C. WILLIAM, DICKEY, BURTON F · 2010 to 2013
$2.0MMechanisms of beta-blocker induced improvements in asthmaR01AI079236 · NIAID · UNIVERSITY OF HOUSTON · PI BOND, RICHARD AGUSTIN · 2009 to 2010
$1.0MNHLBI NIH HHS R01 HL097000NHLBI NIH HHS R01 HL129795NIAID NIH HHS R01 AI079236NIAID NIH HHS R01 AI110007NIAID NIH HHS T32 AI053831
Abstract
The mostly widely used bronchodilators in asthma therapy are β
Indexed as
Adrenergic beta-2 Receptor AntagonistsAnimalsAsthmaBronchiDisease Models, AnimalEosinophilsEpinephrineEpithelial CellsHumansInflammationInterleukin-13LungMetaplasiaMice, Inbred C57BLMice, TransgenicPneumoniaAdrenergic beta-2 Receptor AntagonistsEpinephrineInterleukin-13Receptors, Adrenergic, beta-2airway epitheliumairway hyperresponsivenessasthmamucous metaplasiaβ2-adrenoceptor
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.