Evidence map›Paper›PMID 29073105›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

PAF promotes stemness and radioresistance of glioma stem cells.

Derrick Sek Tong Ong, Baoli Hu, Yan Wing Ho, Charles-Etienne Gabriel Sauvé, Christopher A Bristow, Qianghu Wang, Asha S Multani, Peiwen Chen, Luigi Nezi, Shan Jiang and 13 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
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  3. NFATc3 Enhances DREAM Complex-Driven Transactivation.bioRxiv : the preprint server for biology · 2026
    Article
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  8. METTL8 links mt-tRNA mCell death & disease · 2024
    Article
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  12. A FRET-Based Assay for the Identification of PCNA Inhibitors.International journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 4 institutions in 3 countries.

Derrick Sek Tong OngDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Baoli HuDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Yan Wing HoDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Charles-Etienne Gabriel SauvéDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Christopher A BristowInstitute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Qianghu WangDepartment of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Asha S MultaniDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Peiwen ChenDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Luigi NeziDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Shan JiangInstitute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Claire Elizabeth GormanDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Marta Moreno MonasterioDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Dimpy KoulDepartment of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Matteo MarchesiniDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Simona CollaDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Eun-Jung JinDepartment of Biological Sciences, Wonkwang University, Iksan, CB, 570-749, Korea.
Erik P SulmanDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Denise J SpringDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Wai-Kwan Alfred YungDepartment of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Roel G W VerhaakThe Jackson Laboratory, Farmington, CT 06032.
Lynda ChinDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Y Alan WangDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; yalanwang@mdanderson.org rdepinho@mdanderson.org.
Ronald A DePinhoDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; yalanwang@mdanderson.org rdepinho@mdanderson.org.
The University of Texas MD Anderson Cancer Center · USChildren's Hospital of Pittsburgh · USJackson Laboratory · USWonkwang University · KR

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
TELOMERASE IN DEVELOPMENT, SENESCENCE AND NEOPLASIAR01CA084628 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DEPINHO, RONALD ANTHONY · 2000 to 2019
$10.5M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA084628
6 · The paper itself

Abstract

An integrated genomic and functional analysis to elucidate DNA damage signaling factors promoting self-renewal of glioma stem cells (GSCs) identified proliferating cell nuclear antigen (PCNA)-associated factor (

Indexed as

AnimalsBrain NeoplasmsCarrier ProteinsDNA-Binding ProteinsDNA DamageDNA RepairDNA ReplicationFemaleGene Expression Regulation, NeoplasticGlioblastomaGreen Fluorescent ProteinsHumansMice, SCIDNeoplastic Stem CellsPyrimidinesRadiation ToleranceCarrier ProteinsDNA-Binding ProteinsGreen Fluorescent ProteinsPCLAF protein, humanpyrimidinePyrimidinesDNA translesion synthesisglioma stem cellsself-renewal

Identifiers

PMID29073105
PMCPMC5664518
OpenAlexW2760992476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.