Evidence map›Paper›PMID 29073092›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Unique amalgamation of primary and secondary structural elements transform peptaibols into potent bioactive cell-penetrating peptides.

Lin Du, April L Risinger, Carter A Mitchell, Jianlan You, Blake W Stamps, Ning Pan, Jarrod B King, Jean C Bopassa, Susan I V Judge, Zhibo Yang and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Draft genome sequence of the peptaibol producerMicrobiology resource announcements · 2026
    Article
  2. Article
  3. Article
  4. Genome-Guided Metabolomic Profiling of Peptaibol-ProducingInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Peptaibol Production and Characterization fromJournal of fungi (Basel, Switzerland) · 2022
    Article
  10. Review
  11. Review
  12. Rare Glutamic Acid Methyl Ester Peptaibols fromInternational journal of molecular sciences · 2021
    Article
  13. Article
  14. Article
  15. Monitoring the Site-Specific Solid-State NMR Data in Oligopeptides.International journal of molecular sciences · 2020
    Article
  16. Article
  17. Engineering an ABScientific reports · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Lin DuDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019-5251.
April L RisingerDepartment of Pharmacology, University of Texas Health Science Center, San Antonio, TX 78229.
Carter A MitchellDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019-5251.
Jianlan YouDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019-5251.
Blake W StampsDepartment of Microbiology and Plant Biology, University of Oklahoma, Norman, OK 73019-5251.
Ning PanDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019-5251.
Jarrod B KingDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019-5251.
Jean C BopassaDepartment of Physiology, School of Medicine, University of Texas Health Science Center, San Antonio, TX 78229.
Susan I V JudgeDepartment of Biochemistry, High Throughput Screening Facility, Center for Innovative Drug Discovery, University of Texas Health Science Center, San Antonio, TX 78229.
Zhibo YangDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019-5251.
Bradley S StevensonDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019-5251.
Robert H CichewiczDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019-5251; rhcichewicz@ou.edu.ORCID 0000-0003-0744-4117
University of Oklahoma · USThe University of Texas Health Science Center at San Antonio · US

Funding

Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
Sourcing Bioactive Secondary Metabolites from Great Lakes FungiR01GM107490 · NIGMS · UNIVERSITY OF OKLAHOMA · PI CICHEWICZ, ROBERT HENRY, MOOBERRY, SUSAN L · 2014 to 2017
$2.3M
Degradation of Mitochondrial Inner Membrane Protein Disrupts the Structural Interaction between Mitofilin and Cyclophilin D and Determines the Extent of Ischemia/reperfusion injuryR01HL138093 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BOPASSA, JEAN CHRISOSTOME · 2017 to 2021
$1.9M
From Single Cells to Tissues: a Novel Mass Spectrometry Approach for BioanalysisR01GM116116 · NIGMS · UNIVERSITY OF OKLAHOMA · PI YANG, ZHIBO · 2015 to 2019
$1.5M
NCATS NIH HHS UL1 TR001120NHLBI NIH HHS R01 HL138093NIGMS NIH HHS R01 GM107490NIGMS NIH HHS R01 GM116116
6 · The paper itself

Abstract

Mass-spectrometry-based metabolomics and molecular phylogeny data were used to identify a metabolically prolific strain of

Indexed as

AscomycotaFungal ProteinsGenome, FungalMetabolomicsModels, MolecularPeptaibolsProtein ConformationSpectrometry, Mass, Electrospray IonizationFungal ProteinsPeptaibolsfungigichigaminmitochondrianatural productspeptaibol

Identifiers

PMID29073092
PMCPMC5664515
OpenAlexW2763033036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.