ArticleProceedings of the National Academy of Sciences of the United States of America2017
Pressure effects on collective density fluctuations in water and protein solutions.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Residue-Specific Structural and Dynamical Coupling of Protein and Hydration Water Revealed by Molecular Dynamics Simulations.Biomolecules · 2025Article
- Computational modelling of extrusion process temperatures on the interactions between black soldier fly larvae protein and corn flour starch.Food chemistry. Molecular sciences · 2024Article
- Combined Effects of Pressure and Ionic Strength on Protein-Protein Interactions: An Empirical Approach.Biomacromolecules · 2024Article
- High pressure inhibits signaling protein binding to the flagellar motor and bacterial chemotaxis through enhanced hydration.Scientific reports · 2020Article
- Structural Relaxation Processes and Collective Dynamics of Water in Biomolecular Environments.The journal of physical chemistry. B · 2019Article
- Towards developing principles of protein folding and dynamics in the cell.Physical biology · 2018Review
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Authors and funding
4 authors.
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Abstract
Neutron Brillouin scattering and molecular dynamics simulations have been used to investigate protein hydration water density fluctuations as a function of pressure. Our results show significant differences between the pressure and density dependence of collective dynamics in bulk water and in concentrated protein solutions. Pressure-induced changes in the tetrahedral order of the water HB network have direct consequences for the high-frequency sound velocity and damping coefficients, which we find to be a sensitive probe for changes in the HB network structure as well as the wetting of biomolecular surfaces.
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