Evidence map›Paper›PMID 29073030›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Expanded subgenomic mRNA transcriptome and coding capacity of a nidovirus.

Han Di, Joseph C Madden, Esther K Morantz, Hsin-Yao Tang, Rachel L Graham, Ralph S Baric, Margo A Brinton

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 34 citations in OpenAlex.

  1. Discovery of the order 'Virus evolution · 2026
    Article
  2. Article
  3. Giant RNA genomes: Roles of host, translation elongation, genome architecture, and proteome in nidoviruses.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Classification, replication, and transcription ofFrontiers in microbiology · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. A nidovirus perspective on SARS-CoV-2.Biochemical and biophysical research communications · 2021
    Review
  19. Article
  20. The molecular virology of coronaviruses.The Journal of biological chemistry · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Han DiDepartment of Biology, Georgia State University, Atlanta, GA 30303.
Joseph C MaddenDepartment of Biology, Georgia State University, Atlanta, GA 30303.
Esther K MorantzDepartment of Biology, Georgia State University, Atlanta, GA 30303.
Hsin-Yao TangProteomics and Metabolomics Facility, The Wistar Institute, Philadelphia, PA 19104.
Rachel L GrahamDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Ralph S BaricDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Margo A BrintonDepartment of Biology, Georgia State University, Atlanta, GA 30303; mbrinton@gsu.edu.ORCID 0000-0003-4868-175X
Georgia State University · USUniversity of North Carolina at Chapel Hill · USThe Wistar Institute · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Study of Novel HHV8/KSHV Encoded GenesU19AI107810 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DITTMER, DIRK P · 2013 to 2017
$10.6M
Development of a new model of viral hemorrhagic fever. R21AI073824 · NIAID · GEORGIA STATE UNIVERSITY · PI BRINTON, MARGO A · 2007 to 2008
$358k
NIAID NIH HHS R21 AI073824NIAID NIH HHS U19 AI107810NIH HHS P51 OD011132
6 · The paper itself

Abstract

Members of the order Nidovirales express their structural protein ORFs from a nested set of 3' subgenomic mRNAs (sg mRNAs), and for most of these ORFs, a single genomic transcription regulatory sequence (TRS) was identified. Nine TRSs were previously reported for the arterivirus

Indexed as

Regulatory Sequences, Ribonucleic AcidAnimalsBlotting, NorthernChlorocebus aethiopsCodon, InitiatorGenome, ViralMacacaMutationNidoviralesNidovirales InfectionsOpen Reading FramesRNA, MessengerRNA, ViralViral ProteinsViral Structural ProteinsCodon, InitiatorRegulatory Sequences, Ribonucleic AcidRNA, MessengerRNA, ViralViral ProteinsViral Structural Proteinsnext-generation sequencingnidovirusSimian hemorrhagic fever virussubgenomic mRNAstranscription regulatory sequences

Identifiers

PMID29073030
PMCPMC5651751
OpenAlexW2761634972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.