Evidence map›Paper›PMID 29072124›Full record

ArticleAmerican journal of men's health2018

Efficacy of Low-Intensity Extracorporeal Shock Wave Therapy on Men With Chronic Pelvic Pain Syndrome Refractory to 3-As Therapy.

Shiao-Jin Guu, Jiun-Hung Geng, I-Ting Chao, Hui-Tzu Lin, Yung-Chin Lee, Yung-Shun Juan, Chia-Chu Liu, Chii-Jye Wang, Chia-Chun Tsai

Open access · goldAbstract read
In one paragraph

Article in American journal of men's health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Shiao-Jin Guu1 Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Jiun-Hung Geng1 Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
I-Ting Chao3 Teaching and Research Center, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.
Hui-Tzu Lin3 Teaching and Research Center, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.
Yung-Chin Lee1 Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Yung-Shun Juan1 Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chia-Chu Liu1 Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chii-Jye Wang1 Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chia-Chun Tsai1 Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Kaohsiung Medical University · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWKaohsiung Municipal Ta-Tung Hospital · TWKaohsiung Municipal Hsiao-Kang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Managing patients with chronic pelvic pain syndrome (CPPS) refractory to the traditional 3-As therapy (antibiotics, alpha-blockers, and anti-inflammatories) is a challenging task. Low-intensity extracorporeal shock wave therapy (LI-ESWT) was recently reported to be able to improve pain, urinary symptoms, and even sexual function by inducing neovascularization and anti-inflammation, reducing muscle tone, and influencing nerve impulses. This study evaluates whether combined treatment with LI-ESWT can restore clinical ability and quality of life (QoL) in patients refractory to 3-As therapy. This was an open-label, single-arm prospective study. Patients with CPPS without more than a 6-point decrease in the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) total score under the maximal dosage of 3-As therapy were enrolled. LI-ESWT treatment consisted of 3,000 shock waves administered once weekly for 4 weeks. The NIH-CPSI, visual analog scale (VAS) score, International Prostate Symptom Score (IPSS), and the five-item version of the International Index of Erectile Function (IIEF-5) were used to evaluate efficacy at 1, 4, and 12 weeks after LI-ESWT. Thirty-three patients were enrolled in this study. After LI-ESWT treatment, 27 of the 33 patients (81.82%) had a successful response to LI-ESWT, with a decrease of 3.29 and 5.97 in the VAS score and total IPSS at the 3-month follow-up. Waist circumference was the only significant predictor of a successful response to LI-ESWT. LI-ESWT can serve as a salvage therapy for patients with CPPS refractory to traditional 3-As therapy. Further studies are needed to determine an adequate therapeutic protocol and important predictors in patients with different CPPS etiologies.

Indexed as

Extracorporeal Shockwave TherapyAdrenergic alpha-AntagonistsAdultAnti-Bacterial AgentsAnti-Inflammatory AgentsChronic PainHumansMaleMiddle AgedPelvic PainProspective StudiesTaiwanTreatment FailureAdrenergic alpha-AntagonistsAnti-Bacterial AgentsAnti-Inflammatory Agents3-As therapychronic pelvic pain syndromeshock wave therapy

Identifiers

PMID29072124
PMCPMC5818120
OpenAlexW2765299618

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.