Evidence map›Paper›PMID 29071557›Full record

ReviewInternational urology and nephrology2018

Collectins in urinary tract and kidney diseases.

Yongfang Qin, Jingjing Liu, Jiao Liu, Fengqi Hu

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yongfang QinDepartment of Nephrology, Xiangyang Central Hospital, Hubei University of Arts and Science, Xiangyang, 441000, Hubei, China.
Jingjing LiuDepartment of Nephrology, Xiangyang Central Hospital, Hubei University of Arts and Science, Xiangyang, 441000, Hubei, China.
Jiao LiuDepartment of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei, China.
Fengqi HuDepartment of Nephrology, Xiangyang Central Hospital, Hubei University of Arts and Science, Xiangyang, 441000, Hubei, China. hufengqi1@gmail.com.
Xiangyang Central Hospital · CNHubei University of Arts and Science · CNWuhan University · CN

Funding

Hubei Province Health and Family Planning Scientific Research Project WJ2015Q038National Natural Science Foundation of China 81300617
6 · The paper itself

Abstract

The innate immune system serves as the frontline defense against invading pathogens and initiates an inflammatory response to microorganisms. Collectins are C-type lectins that are structurally characterized by a collagen-like sequence and a carbohydrate recognition domain. Moreover, they are widely expressed throughout the body and are involved in the innate immunity against a variety of pathogens, regulating inflammation, and protecting the lungs from pathogens. Recently, two classical collectins, surfactant protein A (SP-A) and surfactant protein D (SP-D), as well as novel collectin 11, were found present in urinary tract tissues. They are increasingly recognized as key players in activating the humoral arm of innate immunity and host defense in urinary tract and kidney diseases, although their biological features, functions, and mechanisms in this regard remain largely unclear. In this review, we aim to integrate results reported by ourselves and others to summarize and gain a better understanding of the functions of collectins (SP-A, SP-D, and collectin 11) in urinary tract and kidney diseases.

Indexed as

Acute Kidney InjuryAtherosclerosisCollectinsFibrosisHumansImmunity, InnateKidneyPulmonary Surfactant-Associated Protein APulmonary Surfactant-Associated Protein DUrinary TractUrinary Tract InfectionsColec11 protein, humanCollectinsPulmonary Surfactant-Associated Protein APulmonary Surfactant-Associated Protein DCollectin 11Host defenseInnate immunitySurfactant protein ASurfactant protein D

Identifiers

PMID29071557
OpenAlexW2766102084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.