Evidence map›Paper›PMID 29071515›Full record

ArticleInflammation2018

Systemic Inflammatory Response and Multiple Organ Dysfunctions Following Crush Injury: a New Experimental Model in Rabbits.

Peng Xu, Fei Wang, Xian-Long Zhou, Lei Li, Dan Xiong, Yong-Quan Yong, Yan Zhao, Wang-Xiang Jiang

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Peng XuEmergency Center, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan, Hubei, 430071, China.
Fei WangWuhan Medical Emergency Center, 10 Xinhua Road, Wuhan, Hubei, 430000, China.
Xian-Long ZhouEmergency Center, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan, Hubei, 430071, China.
Lei LiEmergency Center, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan, Hubei, 430071, China.
Dan XiongEmergency Center, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan, Hubei, 430071, China.
Yong-Quan YongWuhan Medical Emergency Center, 10 Xinhua Road, Wuhan, Hubei, 430000, China. yyx2014@163.com.
Yan ZhaoEmergency Center, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan, Hubei, 430071, China. doctoryanzhao@163.com.
Wang-Xiang JiangWuhan Medical Emergency Center, 10 Xinhua Road, Wuhan, Hubei, 430000, China.
Zhongnan Hospital of Wuhan University · CNWuhan University · CN

Funding

Emergency Diagnostic & Therapeutic Center of Central China (Wuhan, Hubei, China) NAHealth and Family Planning Commission of Hubei Province WJ2015Z073Health and Family Planning Commission of Wuhan City VX15D53
6 · The paper itself

Abstract

In this study, we aim to develop a new, reproducible crush injury (CI) model in rabbits. Anesthetized rabbits were compressed on both hind limbs using a special instrument for 6 h followed by 3 h of reperfusion. Blood samples and injured muscles were collected for biochemical analysis and morphological evaluation. Survival observation lasted for 72 h. Bilateral compressions with 10 kg/kg body weight (BW), but not with 5 kg/kg BW, reduced serious systemic impairment. Bilateral compressions with 10 kg/kg BW resulted in severe lactic acidosis; increased serum K

Indexed as

AnimalsBiomarkersBody Temperature RegulationBody WeightCarbon DioxideCrush InjuriesCytokinesDisease Models, AnimalHemodynamicsHindlimbInflammationInflammation MediatorsInterleukin-10Interleukin-1betaInterleukin-4Lactic AcidBiomarkersCarbon DioxideCytokinesIL1B protein, ratInflammation MediatorsInterleukin-10Interleukin-1betaInterleukin-4Lactic AcidOxygenPotassiumTumor Necrosis Factor-alphacrush injuryexperimental modelinflammatory responserabbit

Identifiers

PMID29071515
OpenAlexW2766038633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.