Evidence map›Paper›PMID 29071479›Full record

ArticleZeitschrift fur Gerontologie und Geriatrie2018

Association of potentially inappropriate medications with outcomes of inpatient geriatric rehabilitation : A prospective cohort study.

Madeleine Bachmann, Jan Kool, Peter Oesch, Marcel Weber, Stefan Bachmann

Abstract read
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In one paragraph

Article in Zeitschrift fur Gerontologie und Geriatrie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Madeleine BachmannKlinik für Rheumatologie und internistische Rehabilitation, Rehabilitation Center Kliniken Valens, Taminaplatz 1, 7317, Valens, Switzerland.
Jan KoolKlinik für Rheumatologie und internistische Rehabilitation, Rehabilitation Center Kliniken Valens, Taminaplatz 1, 7317, Valens, Switzerland.
Peter OeschKlinik für Rheumatologie und internistische Rehabilitation, Rehabilitation Center Kliniken Valens, Taminaplatz 1, 7317, Valens, Switzerland.
Marcel WeberKlinik für Rheumatologie, Stadtspital Triemli, Birmensdorferstraße 497, 8063, Zürich, Switzerland.
Stefan BachmannKlinik für Rheumatologie und internistische Rehabilitation, Rehabilitation Center Kliniken Valens, Taminaplatz 1, 7317, Valens, Switzerland. stefan.bachmann@kliniken-valens.ch.ORCID http://orcid.org/0000-0003-2164-0122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigher age is associated with multimorbidity, which may lead to polypharmacy and potentially inappropriate medication (PIM).

objectiveTo evaluate whether PIM on admission for geriatric inpatient rehabilitation is associated with rehabilitation outcome regarding mobility and quality of life. MATERIAL AND

methodsA total of 210 patients were included. Medications at hospital admission were analyzed with the Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) and the number of PIMs individual patients were taking was determined. The study population was then divided into two groups, one with and one without PIM. The main rehabilitation outcomes, quality of life and mobility, were assessed on admission and discharge. Associations between PIM and the main outcomes were analyzed using the two-tailed Student's t-test and Spearman correlations.

resultsIn total 131 PIMs were identified by STOPP. Of the patients 91 (43%) were taking at least 1 PIM, and 119 patients (57%) were not taking any PIM. Patients with no PIM had a significantly better quality of life on admission (p < 0.05) and discharge (p < 0.005). The number of PIMs was not associated with the rehabilitation outcomes mobility and quality of life (Spearman's ρ = -0.01, p = 0.89 and ρ = -0.02, p = 0.7, respectively). The quality of life and mobility increased identically in both groups from admission to discharge but the group with PIM did not reach the levels of those without PIM.

conclusionThe use of PIM may have a negative impact on the quality of life of elderly people but patients with and without PIM achieved comparable improvements in quality of life and mobility. Further studies are required to assess the long-term outcomes of patients taking PIM following inpatient rehabilitation.

Indexed as

Inappropriate PrescribingInpatientsPotentially Inappropriate Medication ListRehabilitationActivities of Daily LivingAgedAged, 80 and overCohort StudiesFemaleHumansMaleProspective StudiesQuality of LifeMobilityOutcome assessmentProspective studyQuality of lifeRehabilitation

Identifiers

PMID29071479
PMCPMC6244995

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.