Evidence map›Paper›PMID 29071298›Full record

ArticleeNeuro

Unique Configurations of Compression and Truncation of Neuronal Activity Underlie l-DOPA-Induced Selection of Motor Patterns in

Curtis L Neveu, Renan M Costa, Ryota Homma, Shin Nagayama, Douglas A Baxter, John H Byrne

Abstract readVideo-Audio Media
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Successful and unsuccessful attempts to swallow in a reducedLearning & memory (Cold Spring Harbor, N.Y.) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Curtis L NeveuDepartment of Neurobiology and Anatomy, W. M. Keck Center for the Neurobiology of Learning and Memory, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX 77030.ORCID 0000-0003-3291-7537
Renan M CostaDepartment of Neurobiology and Anatomy, W. M. Keck Center for the Neurobiology of Learning and Memory, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX 77030.ORCID 0000-0001-7195-5259
Ryota HommaDepartment of Neurobiology and Anatomy, W. M. Keck Center for the Neurobiology of Learning and Memory, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX 77030.
Shin NagayamaDepartment of Neurobiology and Anatomy, W. M. Keck Center for the Neurobiology of Learning and Memory, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX 77030.
Douglas A BaxterDepartment of Neurobiology and Anatomy, W. M. Keck Center for the Neurobiology of Learning and Memory, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX 77030.
John H ByrneDepartment of Neurobiology and Anatomy, W. M. Keck Center for the Neurobiology of Learning and Memory, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX 77030.ORCID 0000-0001-7947-5890

Funding

Analyses of the Distributed Representation of Associative-Learning in an Identified Circuit Using a Combination of Single-Cell Electrophysiology and Multicellular Voltage-Sensitive Dye RecordingsR01NS101356 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI John H Byrne · 2018 to 2026
$3.2M
NINDS NIH HHS R01 NS101356
6 · The paper itself

Abstract

A key issue in neuroscience is understanding the ways in which neuromodulators such as dopamine modify neuronal activity to mediate selection of distinct motor patterns. We addressed this issue by applying either low or high concentrations of l-DOPA (40 or 250 μM) and then monitoring activity of up to 130 neurons simultaneously in the feeding circuitry of

Indexed as

Action PotentialsAnimalsAplysiaAxonsChoice BehaviorDopamine AgentsDose-Response Relationship, DrugFeeding BehaviorFunctional LateralityGanglia, InvertebrateLevodopaMotor ActivityMotor NeuronsNeural PathwaysReaction TimeVoltage-Sensitive Dye ImagingDopamine AgentsLevodopaAplysiacentral pattern generatorl-DOPAvoltage-sensitive dye

Identifiers

PMID29071298
PMCPMC5654236

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.