Evidence map›Paper›PMID 29071197›Full record

ArticleNanotheranostics2017

Amplified visual immunosensor integrated with nanozyme for ultrasensitive detection of avian influenza virus.

Syed Rahin Ahmed, Juan C Corredor, Éva Nagy, Suresh Neethirajan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanotheranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Syed Rahin AhmedBioNano Laboratory, School of Engineering, University of Guelph, Guelph, Ontario, Canada N1G 2W1.
Juan C CorredorDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1.
Éva NagyDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1.
Suresh NeethirajanBioNano Laboratory, School of Engineering, University of Guelph, Guelph, Ontario, Canada N1G 2W1.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanomaterial-based artificial enzymes or nanozymes exhibit superior properties such as stability, cost effectiveness and ease of preparation in comparison to conventional enzymes. However, the lower catalytic activity of nanozymes limits their sensitivity and thereby practical applications in the bioanalytical field. To overcome this drawback, herein we propose a very simple but highly sensitive, specific and low-cost dual enhanced colorimetric immunoassay for avian influenza A (H5N1) virus. 3,3´,5,5´- Tetramethylbenzidine (TMBZ) was used as a reducing agent to produce gold nanoparticles (Au NPs) with blue colored solution from a viral target-specific antibody-gold ion mixture at first step. The developed blue color from the sensing design was further amplified through catalytic activity of Au NPs in presence of TMBZ-hydrogen peroxide (H

Indexed as

Avian influenza virus detectionDual color enhancementGold nanoparticlesPeroxidase mimic

Identifiers

PMID29071197
PMCPMC5646732

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.