Evidence map›Paper›PMID 29071164›Full record

ArticleEngineering (Beijing, China)2017

Biophysical Regulation of Cell Behavior-Cross Talk between Substrate Stiffness and Nanotopography.

Yong Yang, Kai Wang, Xiaosong Gu, Kam W Leong

Abstract read
In one paragraph

Article in Engineering (Beijing, China), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed.

  1. Review
  2. Article
  3. 3D Printing Strategies for Bioengineering Human Cornea.Advanced healthcare materials · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Skeletal Muscle Tissue Engineering: From Tissue Regeneration to Biorobotics.Cyborg and bionic systems (Washington, D.C.) · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yong YangDepartment of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV 26506, USA.
Kai WangDepartment of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV 26506, USA.
Xiaosong GuKey Laboratory of Neuroregeneration of Jiangsu and the Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu 226001, China.
Kam W LeongDepartment of Biomedical Engineering, Columbia University, New York, NY 10027, USA.

Funding

Interaction of Subchondral Bone and Articular Cartilage System with Skeletal MuscleUH3TR000505 · NCATS · DUKE UNIVERSITY · PI TRUSKEY, GEORGE A · 2014 to 2016
$3.6M
Oral Therapy for Hemophilia AR01HL109442 · NHLBI · UNIVERSITY OF FLORIDA · PI DANIELL, HENRY, HERZOG, ROLAND W. · 2011 to 2015
$3.5M
Overcoming Immunosenescence by Nanoparticle-Mediated ActivationR01AI096305 · NIAID · DUKE UNIVERSITY · PI ABRAHAM, SOMAN N, LEONG, KAM W · 2012 to 2016
$1.8M
A synthetic biology approach to analyze evolution of programmed bacterial deathR01GM110494 · NIGMS · DUKE UNIVERSITY · PI YOU, LINGCHONG · 2014 to 2017
$1.2M
Biomimetic Alveolar Interstitium Model for Investigation of Nanomaterials-induced FibrogenesisR15GM122953 · NIGMS · WEST VIRGINIA UNIVERSITY · PI YANG, YONG · 2016 to 2016
$431k
NCATS NIH HHS UH3 TR000505NHLBI NIH HHS R01 HL109442NIAID NIH HHS R01 AI096305NIGMS NIH HHS R01 GM110494NIGMS NIH HHS R15 GM122953
6 · The paper itself

Abstract

The stiffness and nanotopographical characteristics of the extracellular matrix (ECM) influence numerous developmental, physiological, and pathological processes

Indexed as

Adhesive ligandsCell behaviorExtracellular matrixNanotopographyStiffness

Identifiers

PMID29071164
PMCPMC5653318

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.