Evidence map›Paper›PMID 29071061›Full record

ArticleClinics and practice2017

Gut microbiota's effect on mental health: The gut-brain axis.

Megan Clapp, Nadia Aurora, Lindsey Herrera, Manisha Bhatia, Emily Wilen, Sarah Wakefield

Registry-linked trialAbstract read
In one paragraph

Article in Clinics and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06905223 (A Pilot Study on the Efficacy of a Synbiotic Formula), which is not on this map. Cited by 278 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
278citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06905223 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Pilot Study on the Efficacy of a Synbiotic Formula (MQU10) in Improving Mood and Well-being in Adults With Mild to Moderate Depressive Symptoms

TypeinterventionalSponsorGenieBiome LimitedRan2025 to 2027Enrolled30ConditionsDepressive Symptoms Mild to Moderate in SeverityArmsMQU10
3 · Its place in the literature

Who cites it

278 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Nutraceuticals in Psychiatric Disorders: A Systematic Review.International journal of molecular sciences · 2024
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. The Impact ofNutrients · 2025
    Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Placebo-resistant gut bacteria:Frontiers in cellular and infection microbiology · 2024
    Trial
  15. Review
  16. Antioxidant and Anti-Inflammatory Effects of InhaledPlants (Basel, Switzerland) · 2026
    Article
  17. Review
  18. Review
  19. Article
  20. Article

218 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Megan ClappSchool of Medicine.
Nadia AuroraSchool of Medicine.
Lindsey HerreraSchool of Medicine.
Manisha BhatiaSchool of Medicine.
Emily WilenSchool of Medicine.
Sarah WakefieldDepartment of Psychiatry, Health Sciences Center, Texas Tech University, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anxietydepressiondysbiosisgut-brain-axisMicrobiome

Identifiers

PMID29071061
PMCPMC5641835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.