ArticleClinical interventions in aging2017
Evaluation of various equations for estimating renal function in elderly Chinese patients with type 2 diabetes mellitus.
Article in Clinical interventions in aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Diagnostic value of the Modification of Diet in Renal Disease and Chronic Kidney Disease Epidemiology Collaboration equations in diabetic patients: a systematic review and meta-analysis.The Journal of international medical research · 2020Pooled it
- Serum total protein-to-albumin ratio and adverse clinical outcomes in patients with diabetes and chronic kidney disease: a comparative study of US and Chinese cohorts.International urology and nephrology · 2026Article
- Guideline for the Management of Diabetes Mellitus in the Elderly in China (2024 Edition).Aging medicine (Milton (N.S.W)) · 2024Article
- Comparative Determination of Glomerular Filtration Rate Estimation Formulae in Type 2 Diabetic Patients: An Observational Study.BioMed research international · 2024Observational
- Association between renal function and bone mineral density in patients with type 2 diabetes mellitus.Heliyon · 2023Article
- Concordance and Discrepancies Among 5 Creatinine-Based Equations for Assessing Estimated Glomerular Filtration Rate in Older Adults.JAMA network open · 2023Article
- Association between kidney function and biological age: a China Health and Retirement Longitudinal Study.Frontiers in public health · 2023Article
- Risk factor analysis and clinical decision tree model construction for diabetic retinopathy in Western China.World journal of diabetes · 2022Article
- The Predicted Value of Kidney Injury Molecule-1 (KIM-1) in Healthy People.International journal of general medicine · 2022Article
- Analysis of risk factors for carotid intima-media thickness in patients with type 2 diabetes mellitus in Western China assessed by logistic regression combined with a decision tree model.Diabetology & metabolic syndrome · 2020Article
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Authors and funding
8 authors at 4 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe clinical assessment of kidney function based on the estimated glomerular filtration rate (GFR) in older patients remains controversial. This study evaluated the concordance and feasibility of using various creatinine-based equations for estimating GFR in elderly Chinese patients with type 2 diabetes mellitus (T2DM).
methodsA cross-sectional analytical study was conducted in 21,723 older diabetic patients (≥60 years) based on electronic health records (EHR) for Minhang District, Shanghai, China. The concordance of chronic kidney disease (CKD) classification among different creatinine-based equations was assessed based on Kappa values, intraclass correlation coefficient (ICC) statistics, and the eGFR agreement between the equations was tested using Bland-Altman plots. The GFR was estimated using the Cockcroft-Gault (CG), Berlin Initiative Study 1 (BIS1), simplified Modification of Diet in Renal Disease (MDRD), MDRD modified for Chinese populations (mMDRD), chronic kidney disease epidemiology collaboration (CKD-EPI), CKD-EPI in Asians (CKD-EPI-Asia), and Ruijin equations.
resultsOverall, the proportion of CKD stages 3-5 (eGFR <60 mL/min/1.73 m
conclusionAccurate GFR values are difficult to estimate using creatinine-based equations in older diabetic patients. Kidney function is complex, and the staff need to be aware of the individualized consideration of other risk factors or markers of reduced renal function in clinical practice.
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