ArticleScientific reports2017
Synergistic acceleration of experimental tooth movement by supplementary high-frequency vibration applied with a static force in rats.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Effect of vibration on orthodontic tooth movement in a double blind prospective randomized controlled trial.Scientific reports · 2022Trial
- Synergistic effects of high-frequency vibration and orthodontic force on osteoclast numbers and root resorption in a rat model.The Angle orthodontist · 2025Article
- Salivary Proteomics & Gene Expression Analysis: Applications in Orthodontics and Oral Health Care Research-A Pilot Project.Biomarker insights · 2025Article
- Age-related alveolar bone maladaptation in adult orthodontics: finding new ways out.International journal of oral science · 2024Review
- Effects of Vibration on Accelerating Orthodontic Tooth Movement in Clinical and In Vivo Studies: A Systematic Review.Dentistry journal · 2024Review
- The gingival crevicular fluid biomarkers with micropulse vibration device: A pilot study.Heliyon · 2024Article
- Vibrational Force on Accelerating Orthodontic Tooth Movement: A Systematic Review and Meta-Analysis.European journal of dentistry · 2023Article
- Effect of 125 Hz and 150 Hz vibrational frequency electric toothbrushes on the rate of orthodontic tooth movement and prostaglandin E2 levels.Korean journal of orthodontics · 2023Article
- The effect of low-frequency high-intensity ultrasound combined with aspirin on tooth movement in rats.BMC oral health · 2023Article
- The role of TRPV2 as a regulator on the osteoclast differentiation during orthodontic tooth movement in rats.Scientific reports · 2023Article
- Establishment, FEM analysis and experimental validation of tooth movement prediction model of orthodontic archwire T-loop.BMC oral health · 2022Article
- Effects of compressive stress combined with mechanical vibration on osteoclastogenesis in RAW 264.7 cells.The Angle orthodontist · 2022Article
- Examination of the effect of combined use of Er:YAG laser irradiation and mechanical force loading on bone metabolism using primary human gingival fibroblasts.Lasers in medical science · 2020Article
- The Effect of High-Frequency Vibration on Tooth Movement and Alveolar Bone in Non-Growing Skeletal Class II High Angle Orthodontic Patients: Case Series.Dentistry journal · 2020Article
- Comparative assessment of mouse models for experimental orthodontic tooth movement.Scientific reports · 2020Article
- Methionine Enkephalin Suppresses Osteocyte Apoptosis Induced by Compressive Force through Regulation of Nuclear Translocation of NFATc1.JBMR plus · 2020Article
- Delayed tooth movement in Runx2Bone reports · 2020Article
- [Adjunctive interventions to accelerate orthodontic tooth movement].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2019Review
- Effect of high-frequency vibration on orthodontic tooth movement and bone density.Journal of orthodontic science · 2019Article
- Performance comparison of vibration devices on orthodontic tooth movement - A systematic review and meta-analysis.Journal of oral biology and craniofacial researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several recent prospective clinical trials have investigated the effect of supplementary vibration applied with fixed appliances in an attempt to accelerate tooth movement and shorten the duration of orthodontic treatment. Among them, some studies reported an increase in the rate of tooth movement, but others did not. This technique is still controversial, and the underlying cellular and molecular mechanisms remain unclear. In the present study, we developed a new vibration device for a tooth movement model in rats, and investigated the efficacy and safety of the device when used with fixed appliances. The most effective level of supplementary vibration to accelerate tooth movement stimulated by a continuous static force was 3 gf at 70 Hz for 3 minutes once a week. Furthermore, at this optimum-magnitude, high-frequency vibration could synergistically enhance osteoclastogenesis and osteoclast function via NF-κB activation, leading to alveolar bone resorption and finally, accelerated tooth movement, but only when a static force was continuously applied to the teeth. These findings contribute to a better understanding of the mechanism by which optimum-magnitude high-frequency vibration accelerates tooth movement, and may lead to novel approaches for the safe and effective treatment of malocclusion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.