Evidence map›Paper›PMID 29070829›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2018

Hemoglobin A1c and C-reactive protein are independently associated with blunted nocturnal blood pressure dipping in obesity-related prediabetes.

Abbi D Lane-Cordova, Graziela Z Kalil, Christopher J Wagner, Amy L Sindler, Jess G Fiedorowicz, Tiwaloluwa Ajibewa, William G Haynes, Gary L Pierce

Open access · greenAbstract read
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Determinants of pulse pressure amplification in hypertensive and diabetic patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  6. Impaired nocturnal blood pressure dipping in patients with type 2 diabetes mellitus.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Abbi D Lane-CordovaDepartment of Health and Human Physiology, University of Iowa, Iowa City, IA, USA.
Graziela Z KalilDepartment of Health and Human Physiology, University of Iowa, Iowa City, IA, USA.
Christopher J WagnerDepartment of Health and Human Physiology, University of Iowa, Iowa City, IA, USA.
Amy L SindlerDepartment of Health and Human Physiology, University of Iowa, Iowa City, IA, USA.
Jess G FiedorowiczDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA.
Tiwaloluwa AjibewaDepartment of Health and Human Physiology, University of Iowa, Iowa City, IA, USA.
William G HaynesDepartment of Internal Medicine, University of Iowa, Iowa City, IA, USA.
Gary L PierceDepartment of Health and Human Physiology, University of Iowa, Iowa City, IA, USA.
University of Iowa · USFraternal Order of Eagles · USUniversity of South Carolina · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
VASOPRESSIN IN CARDIOVASCULAR REGULATIONP01HL014388 · NHLBI · UNIVERSITY OF IOWA · PI MEYERHOLZ, DAVID K · 1985 to 2018
$40.3M
Multidisciplinary Lung Research Career Development ProgramT32HL007638 · NHLBI · UNIVERSITY OF IOWA · PI WELSH, MICHAEL J., ZABNER, JOSEPH · 1986 to 2020
$16.9M
INTERDISCIPLINARY CARDIOVASCULAR RESEARCH FELLOWSHIPT32HL007121 · NHLBI · UNIVERSITY OF IOWA · PI LONDON, BARRY · 1985 to 2020
$15.1M
The University of Iowa Clinical and Translational Science AwardU54TR001356 · NCATS · UNIVERSITY OF IOWA · PI WINOKUR, PATRICIA · 2015 to 2016
$7.1M
University of Iowa Clinical and Translational Science Program (KL2)KL2RR024980 · NCRR · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2007 to 2011
$4.6M
University of Iowa Institute for Clinical and Translational ScienceU54TR001013 · NCATS · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2014 to 2014
$4.2M
Targeting Inflammation to Treat Cardiovascular Aging in HumansR21AG043722 · NIA · UNIVERSITY OF IOWA · PI PIERCE, GARY L. · 2013 to 2014
$415k
Role of NAD+ Bioavailability in Vascular and Renal Dysfunction in Aging and CKDK01AG047626 · NIA · UNIVERSITY OF IOWA · PI SINDLER, AMY LYNN · 2015 to 2016
$251k
NCATS NIH HHS U54 TR001013NCATS NIH HHS U54 TR001356NCRR NIH HHS KL2 RR024980NHLBI NIH HHS P01 HL014388NHLBI NIH HHS T32 HL007121NHLBI NIH HHS T32 HL007638NIA NIH HHS K01 AG047626NIA NIH HHS R21 AG043722NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

Blunted nocturnal dipping in blood pressure (BP) is associated with increased cardiovascular disease (CVD) risk in middle-aged/older adults. The prevalence of blunted nocturnal BP dipping is higher in persons with obesity and diabetes, conditions that are also associated with elevated aortic stiffness and inflammation. Therefore, we hypothesized that elevated glycemia, inflammation and aortic stiffness would be inversely associated with the magnitude of nocturnal systolic BP dipping among middle-aged/older adults with obesity at high CVD risk. Twenty-four hour ambulatory BP monitoring, aortic stiffness (carotid-femoral pulse wave velocity, CF-PWV), hemoglobin A1c (HbA1c) and inflammation (C-reactive protein, CRP) were measured in 86 middle-aged/older adults with obesity and at least one other CVD risk factor (age 40-74 years; 34 male/52 female; body mass index=36.7±0.5 kg m

Indexed as

AdultAgedBlood GlucoseBlood PressureBlood Pressure Monitoring, AmbulatoryBody Mass IndexCircadian RhythmC-Reactive ProteinCross-Sectional StudiesFemaleGlycated HemoglobinHumansMaleMiddle AgedObesityPrediabetic StateBlood GlucoseC-Reactive ProteinGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID29070829
PMCPMC5836467
OpenAlexW2766674524

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.