ArticleProceedings. Biological sciences2017
A pronounced uterine pro-inflammatory response at parturition is an ancient feature in mammals.
Article in Proceedings. Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Interventions for Infection and Inflammation-Induced Preterm Birth: a Preclinical Systematic Review.Reproductive sciences (Thousand Oaks, Calif.) · 2023Pooled it
- Molecular Mechanism and Pathways of Normal Human Parturition in Different Gestational Tissues: A Systematic Review of Transcriptome Studies.Frontiers in physiology · 2021Pooled it
- Fetal inflammatory signals regulate maternal investment during marsupial pregnancy.PLoS biology · 2026Article
- Individual Genomic Loci, Transcript Levels, and Serum Profiles of Immune and Antioxidant Markers Associated with Bacteria-Induced Abortion in Sheep (Veterinary sciences · 2025Article
- Analysis of Potential Genes, Oxidative, Metabolic, and Hormonal Markers Associated with Postpartum Disorder Susceptibility in Barki Sheep (Veterinary sciences · 2025Article
- Hallmarks of uterine receptivity predate placental mammals.bioRxiv : the preprint server for biology · 2024Article
- The extension of mammalian pregnancy required taming inflammation: Independent evolution of extended placentation in the tammar wallaby.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Immunological uterine response to pig embryos before and during implantation.Reproduction in domestic animals = Zuchthygiene · 2022Review
- Single-cell analysis of prostaglandin E2-induced human decidual cell in vitro differentiation: a minimal ancestral deciduogenic signal†.Biology of reproduction · 2022Article
- Placental Inflammasome mRNA Levels Differ by Mode of Delivery and Fetal Sex.Frontiers in immunology · 2022Article
- Utero-Placental Immune Milieu during Normal and Aglepristone-Induced Parturition in the Dog.Animals : an open access journal from MDPI · 2021Article
- The induction of preterm labor in rhesus macaques is determined by the strength of immune response to intrauterine infection.PLoS biology · 2021Article
- Evolution of Embryo Implantation Was Enabled by the Origin of Decidual Stromal Cells in Eutherian Mammals.Molecular biology and evolution · 2021Article
- The Primacy of Maternal Innovations to the Evolution of Embryo Implantation.Integrative and comparative biology · 2020Article
- Multiomic immune clockworks of pregnancy.Seminars in immunopathology · 2020Review
- Uterine epithelial remodelling during pregnancy in the marsupial Monodelphis domestica (Didelphidae): Implications for mammalian placental evolution.Journal of anatomy · 2020Article
- Evidence for regulation of the complement system during pregnancy being ancient and conserved in mammals.Developmental and comparative immunology · 2020Article
- Cooperative inflammation: The recruitment of inflammatory signaling in marsupial and eutherian pregnancy.Journal of reproductive immunology · 2020Review
- Opossum Mammary Maturation as It Relates to Immune Cell Infiltration and Nutritional Gene Transcription.Integrative organismal biology (Oxford, England) · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Regulating maternal immunity is necessary for successful human pregnancy. Whether this is needed in mammals with less invasive placentation is subject to debate. Indeed, the short gestation times in marsupials have been hypothesized to be due to a lack of immune regulation during pregnancy. Alternatively, the maternal marsupial immune system may be unstimulated in the absence of a highly invasive placenta. Transcripts encoding pro-inflammatory cytokines were found to be overrepresented in the whole uterine transcriptome at terminal pregnancy in the opossum,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.