ReviewEuropean respiratory review : an official journal of the European Respiratory Society2017
Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment.
Review in European respiratory review : an official journal of the European Respiratory Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pathway-Specific Polygenic Risk Scores Identify Obstructive Sleep Apnea-Related Pathways Differentially Moderating Genetic Susceptibility to Coronary Artery Disease.Circulation. Genomic and precision medicine · 2022Pooled it
- Distinct Hypoxemic Profiles of Obstructive Sleep Apnea in Southern Italy: The Living with OSA and CPAP Study.Journal of clinical medicine · 2025Article
- Real-world status of continuous positive airway pressure (CPAP) persistence in patients with sleep apnea syndrome (SAS): a retrospective longitudinal study of administrative claims data in Japan.Sleep & breathing = Schlaf & Atmung · 2025Article
- The role of weight management in sleep disordered breathing.Breathe (Sheffield, England) · 2025Review
- Obstructive Sleep Apnea and Outcomes in Cardiac Surgery: A Systematic Review with Meta-Analytic Synthesis (PROSPERO CRD420251049574).Biomedicines · 2025Review
- A comparative analysis of unsupervised machine-learning methods in PSG-related phenotyping.Journal of sleep research · 2025Article
- Arousal Threshold Score: A New Indicator for Examining the Relationship Between Obstructive Sleep Apnea and Overlap Syndrome - A Retrospective Study.Nature and science of sleep · 2025Article
- Sleep Hypoxemia as a Predictor of Mortality in Patients with Sleep Apnea: A Secondary Analysis of the Sleep Heart Health Study.CHEST pulmonary · 2024Article
- Characterisation of Symptom and Polysomnographic Profiles Associated with Cardiovascular Risk in a Sleep Clinic Population with Obstructive Sleep Apnoea.Nature and science of sleep · 2024Article
- Translation of obstructive sleep apnea pathophysiology and phenotypes to personalized treatment: a narrative review.Frontiers in neurology · 2023Review
- APAP Treatment Acceptance Rate and Cost-Effectiveness of Telemedicine in Patients with Obstructive Sleep Apnea: A Randomized Controlled Trial.Nature and science of sleep · 2023Article
- Obstructive sleep apnea: transition from pathophysiology to an integrative disease model.Journal of sleep research · 2022Review
- Relationship Between CPAP Termination and All-Cause Mortality: A French Nationwide Database Analysis.Chest · 2022Article
- ERS International Virtual Congress 2021: Highlights from the Turkish Thoracic Society Early Career Members.Turkish thoracic journal · 2022Article
- Impact of Desaturation Patterns versus Apnea-Hypopnea Index in the Development of Cardiovascular Comorbidities in Obstructive Sleep Apnea Patients.Nature and science of sleep · 2022Review
- Treatment usage patterns of oral appliances for obstructive sleep apnea over the first 60 days: a cluster analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- CPAP Therapy Termination Rates by OSA Phenotype: A French Nationwide Database Analysis.Journal of clinical medicine · 2021Article
- Breathing Re-Education and Phenotypes of Sleep Apnea: A Review.Journal of clinical medicine · 2021Review
- Gender Phenotyping of Patients with Obstructive Sleep Apnea Syndrome Using a Network Science Approach.Journal of clinical medicine · 2020Article
- Reinventing polysomnography in the age of precision medicine.Sleep medicine reviews · 2020Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In all fields of medicine, major efforts are currently dedicated to improve the clinical, physiological and therapeutic understanding of disease, and obstructive sleep apnoea (OSA) is no exception. The personalised medicine approach is relevant for OSA, given its complex pathophysiology and variable clinical presentation, the interactions with comorbid conditions and its possible contribution to poor outcomes. Treatment with continuous positive airway pressure (CPAP) is effective, but CPAP is poorly tolerated or not accepted in a considerable proportion of OSA patients. This review summarises the available studies on the physiological phenotypes of upper airway response to obstruction during sleep, and the clinical presentations of OSA (phenotypes and clusters) with a special focus on our changing attitudes towards approaches to treatment. Such major efforts are likely to change and expand treatment options for OSA beyond the most common current choices (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.