Evidence map›Paper›PMID 29070554›Full record

ReviewThe American journal of clinical nutrition2017

Dietary iron intake, iron status, and gestational diabetes.

Cuilin Zhang, Shristi Rawal

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in The American journal of clinical nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06104800 (Effect of Weight Loss on Hepcidin Levels and Iron Status in Subjects With Obesity.), which is not on this map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06104800 nacompletednot on this mapstarted 2024, after this paper: background citation

Effect of Weight Loss on Hepcidin Levels and Iron Status in Subjects With Obesity.

TypeinterventionalSponsorInstituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranRan2024 to 2025Enrolled42ConditionsObesity, Iron Deficiency AnemiaArmsCalorie-restricted diet with red meat, Calorie-restricted diet without red meat
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Pooled it
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  9. Prenatal iron overload induces hepatic oxidative stress and ferroptosis in offspring mice.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Cuilin ZhangEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD zhangcu@mail.nih.gov.ORCID http://orcid.org/0000-0002-8014-2708
Shristi RawalEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.ORCID http://orcid.org/0000-0003-2587-4022
Eunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

Risk Factors of Gestational DiabetesZIAHD008889 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI YEUNG, EDWINA · 2009 to 2022
$1.4M
6 · The paper itself

Abstract

Pregnant women are particularly vulnerable to iron deficiency and related adverse pregnancy outcomes and, as such, are routinely recommended for iron supplementation. Emerging evidence from both animal and population-based studies, however, has raised potential concerns because significant associations have been observed between greater iron stores and disturbances in glucose metabolism, including increased risk of type 2 diabetes among nonpregnant individuals. Yet, the evidence is uncertain regarding the role of iron in the development of gestational diabetes mellitus (GDM), a common pregnancy complication which has short-term and long-term adverse health ramifications for both women and their children. In this review, we critically and systematically evaluate available data examining the risk of GDM associated with dietary iron, iron supplementation, and iron status as measured by blood concentrations of several indicators. We also discuss major methodologic concerns regarding the available epidemiologic studies on iron and GDM.

Indexed as

Diabetes, GestationalDietDietary SupplementsFemaleFerritinsHepcidinsHumansIronIron DeficienciesIron, DietaryMeta-Analysis as TopicObservational Studies as TopicPregnancyPregnancy ComplicationsPregnancy OutcomeRandomized Controlled Trials as TopicFerritinsHepcidinsIronIron, DietaryReceptors, Transferrindietary irongestational diabetes mellitusiron statusiron supplementationpregnancy

Identifiers

PMID29070554
PMCPMC5701716
OpenAlexW2766726705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.