Evidence map›Paper›PMID 29070491›Full record

ArticleAmerican journal of physiology. Cell physiology2018

RhoA increases ASIC1a plasma membrane localization and calcium influx in pulmonary arterial smooth muscle cells following chronic hypoxia.

Lindsay M Herbert, Thomas C Resta, Nikki L Jernigan

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

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  12. Acid-Sensing Ion Channels and Mechanosensation.International journal of molecular sciences · 2021
    Review
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  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lindsay M HerbertVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center , Albuquerque, New Mexico.
Thomas C RestaVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center , Albuquerque, New Mexico.
Nikki L JerniganVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center , Albuquerque, New Mexico.
University of New Mexico · US

Funding

Vascular Smooth Muscle Function in Pulmonary HypertensionR01HL111084 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI JERNIGAN, NIKKI L · 2013 to 2022
$3.4M
Vascular Smooth Muscle Signaling in Intermittent Hypoxia-Induced Pulmonary HypertensionR01HL132883 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI RESTA, THOMAS C · 2016 to 2019
$1.5M
NHLBI NIH HHS R01 HL111084NHLBI NIH HHS R01 HL132883
6 · The paper itself

Abstract

Increases in pulmonary arterial smooth muscle cell (PASMC) intracellular Ca

Indexed as

Calcium SignalingAcid Sensing Ion ChannelsAnimalsCell MembraneCells, CulturedChronic DiseaseDisease Models, AnimalFemaleHypertension, PulmonaryHypoxiaMaleMice, Inbred C57BLMice, KnockoutMuscle, Smooth, VascularMyocytes, Smooth MuscleProtein TransportAcid Sensing Ion ChannelsASIC1 protein, mouseAsic1 protein, ratrhoA GTP-Binding ProteinRhoA protein, mouseRhoA protein, ratrho GTP-Binding ProteinsASIC1 traffickingcalcium sensitizationpulmonary hypertensionstore-operated calcium entry

Identifiers

PMID29070491
PMCPMC5866437
OpenAlexW2765509009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.