Evidence map›Paper›PMID 29070467›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2017

[Comparison of postoperative drainage and systemic trauma response after endoscopic and traditional near total thyroidectomy].

Yong-Quan Zhang, Zhi-Chao Li, Fei Chen, Hong-Juan Wang, Qiang Li

Abstract readComparative Study
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Yong-Quan ZhangDepartment of General surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. E-mail: zhangyq2015@qq.com.
Zhi-Chao Li
Fei Chen
Hong-Juan Wang
Qiang Li

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the difference of postoperative drainage and systemic trauma response between endoscopic and traditional near total thyroidectomy to provide the basis for selecting appropriate operative methods.

methodsIn this prospective clinical controlled study, 80 patientsscheduled for near total bilateral thyroidectomy for the first time were divided equally into endoscopic surgery group (group A) and open surgery group (group B). The total drainage volume after operation, postoperative extubation time, and postoperative daily drainage volume were recorded after the operation. The contents of triglyceride (TG) and total protein (TP) were determined in the postoperative drainage fluid onthe first day. The levels of interleukin 6 (IL6), high sensitive C reactive protein (HSCRP), alpha 1 acid glycoprotein (AAG), ceruloplasmin (CER) and haptoglobin (HPT) in venous blood were tested before the operation and on the first day after surgery.

resultsCompared with those in group B, the postoperative drainage volumein group Aincreased significantly (P=0.000) and the postoperative extubation time was significantly prolonged (P=0.000); the mean postoperative daily drainage volume was significantly larger ingroup A than in group B (P=0.000) and tended to decrease with time in both groups. There was no significant difference in the content of triglycerideortotal protein in the drainage fluid between the two groups on the first day after operation (P=0.429 and 0.324, respectively). In both groups, the contents of AAG, ceruloplasmin and haptoglobin on the first postoperative day were all similar with those measurement before operation (P>0.05), but significant variations occurred in the levels of IL6 and HSCRP on the first postoperative day (P=0.000). The serum levels of IL?6 or HS?CRP did not differ significantly between the two groups on the first day after operation (P=0.054 and 0.066, respectively).

conclusionCompared with open surgery, endoscopic near total bilateral thyroidectomyis associated with an increased the volume of postoperative drainage and a prolonged time of extubationbut not an increased systemic trauma response. Therefore, endoscopic surgery can serve as one of the routine options for patients who are concerned with neckscars resulting from open surgeries.

Indexed as

DrainageEndoscopyCeruloplasminC-Reactive ProteinHaptoglobinsHumansInterleukin-6OrosomucoidPostoperative PeriodProspective StudiesThyroidectomyTriglyceridesCeruloplasminC-Reactive ProteinHaptoglobinsIL6 protein, humanInterleukin-6OrosomucoidTriglycerides

Identifiers

PMID29070467
PMCPMC6743955

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.